Multivariate analysis of the population representativeness of related clinical studies

[Display omitted] •We extend GIST for quantifying population representativeness of related studies.•We contribute a method for iteratively characterizing underrepresented patients.•We demonstrated the value of this method using Type 2 diabetes mellitus studies.•Our study confirms knowledge in litera...

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Veröffentlicht in:	Journal of biomedical informatics 2016-04, Vol.60, p.66-76
Hauptverfasser:	He, Zhe, Ryan, Patrick, Hoxha, Julia, Wang, Shuang, Carini, Simona, Sim, Ida, Weng, Chunhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Assessments Biomedical Research - standards Clinical trial Clinical Trials as Topic Community participation Databases, Factual Demography - methods Design analysis Diabetes Mellitus, Type 2 Humans Intervals Knowledge representation Mathematical models Medical Informatics Computing Multivariate Analysis Nutrition Nutrition Surveys Observational Studies as Topic Patient Selection Selection Bias Subgroups
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