Cytotoxic Virulence Predicts Mortality in Nosocomial Pneumonia Due to Methicillin-Resistant Staphylococcus aureus

The current study identified bacterial factors that may improve management of methicillin-resistant Staphylococcus aureus (MRSA) nosocomial pneumonia. Isolates were obtained from 386 patients enrolled in a randomized, controlled study of antibiotic efficacy. Isolates were screened for production of...

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Veröffentlicht in:	The Journal of infectious diseases 2015-06, Vol.211 (12), p.1862-1874
Hauptverfasser:	Rose, Hannah R., Holzman, Robert S., Altman, Deena R., Smyth, Davida S., Wasserman, Gregory A., Kafer, Jared M., Wible, Michelle, Mendes, Rodrigo E., Torres, Victor J., Shopsin, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology BACTERIA Bacterial Toxins - toxicity Cell Line Cell Survival - drug effects Cross Infection - microbiology Cross Infection - mortality Culture Media - toxicity Female Humans Major and Brief Reports Male Methicillin-Resistant Staphylococcus aureus - growth & development Methicillin-Resistant Staphylococcus aureus - isolation & purification Methicillin-Resistant Staphylococcus aureus - pathogenicity Middle Aged Neutrophils - drug effects Pneumonia, Staphylococcal - microbiology Pneumonia, Staphylococcal - mortality Vancomycin - pharmacology Virulence Virulence Factors - analysis Young Adult
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