A Simplified Method for Quantifying Sulfur Mustard Adducts to Blood Proteins by Ultra-High Pressure Liquid Chromatography-Isotope Dilution Tandem Mass Spectrometry

Sulfur mustard binds to reactive cysteine residues, forming a stable sulfur-hydroxyethylthioethyl [S-HETE] adduct that can be used as a long-term biomarker of sulfur mustard exposure in humans. The digestion of sulfur mustard-exposed blood samples with proteinase K following total protein precipitat...

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Veröffentlicht in:	Chemical research in toxicology 2015-02, Vol.28 (2), p.256-261
Hauptverfasser:	Pantazides, Brooke G., Crow, Brian S., Garton, Joshua W., Quiñones-González, Jennifer A., Blake, Thomas A., Thomas, Jerry D., Johnson, Rudolph C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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