Impaired left ventricular filling rate induced by treatment with recombinant interleukin 2 for advanced cancer

BACKGROUND--Immunotherapy with recombinant interleukin 2 (rIL 2) has been extensively used to treat cancer but its use has been hampered by serious side effects including severe hypotension, arrhythmias, and myocardial infarction. OBJECTIVE--To assess the effects of rIL 2 on human left ventricular f...

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Veröffentlicht in:	British Heart Journal 1994-02, Vol.71 (2), p.166-169
Hauptverfasser:	Fragasso, G., Tresoldi, M., Benti, R., Vidal, M., Marcatti, M., Borri, A., Besana, C., Gerundini, P. P., Rugarli, C., Chierchia, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Pressure - drug effects Carcinoma, Renal Cell - physiopathology Carcinoma, Renal Cell - therapy Colonic Neoplasms - physiopathology Drug toxicity and drugs side effects treatment Female Heart Rate - drug effects Humans Interleukin-2 - adverse effects Interleukin-2 - therapeutic use Kidney Neoplasms - physiopathology Kidney Neoplasms - therapy Male Medical sciences Melanoma - physiopathology Middle Aged Neoplasms - therapy Ovarian Neoplasms - physiopathology Pharmacology. Drug treatments Radionuclide Ventriculography Recombinant Proteins - therapeutic use Toxicity: cardiovascular system Ventricular Function, Left - drug effects
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