SUMO Modification Stabilizes Dengue Virus Nonstructural Protein 5 To Support Virus Replication

Small ubiquitin-like modifier (SUMO) participates in a reversible posttranslational modification process (SUMOylation) that regulates a wide variety of cellular processes and plays important roles for numerous viruses during infection. However, the roles of viral protein SUMOylation in dengue virus...

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Veröffentlicht in:	Journal of virology 2016-05, Vol.90 (9), p.4308-4319
Hauptverfasser:	Su, Chan-I, Tseng, Chung-Hsin, Yu, Chia-Yi, Lai, Michael M C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acid Sequence Animals Cell Line Cells, Cultured Dengue - genetics Dengue - metabolism Dengue - virology Dengue virus Dengue Virus - physiology Gene Silencing Humans Molecular Sequence Data Protein Interaction Domains and Motifs Protein Stability RNA Interference Sequence Alignment Sumoylation Ubiquitin-Conjugating Enzymes - genetics Viral Nonstructural Proteins - chemistry Viral Nonstructural Proteins - metabolism Virus Replication Virus-Cell Interactions
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