Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters
The enzyme FASN (fatty acid synthase) is potentially related with hypertension and metabolic dysfunction. FASN is highly expressed in the human placenta. We aimed to investigate the relationship circulating FASN has with blood pressure, maternal metabolism and newborn parameters in healthy pregnant...
Gespeichert in:
| Veröffentlicht in: | Scientific reports 2016-04, Vol.6 (1), p.24167-24167, Article 24167 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 24167 |
|---|---|
| container_issue | 1 |
| container_start_page | 24167 |
| container_title | Scientific reports |
| container_volume | 6 |
| creator | Carreras-Badosa, Gemma Prats-Puig, Anna Puig, Teresa Vázquez-Ruíz, Montserrat Bruel, Monserrat Mendoza, Ericka de Zegher, Francis Ibáñez, Lourdes López-Bermejo, Abel Bassols, Judit |
| description | The enzyme FASN (fatty acid synthase) is potentially related with hypertension and metabolic dysfunction.
FASN
is highly expressed in the human placenta. We aimed to investigate the relationship circulating FASN has with blood pressure, maternal metabolism and newborn parameters in healthy pregnant women. Circulating FASN was assessed in 115 asymptomatic pregnant women in the second trimester of gestation along with C-peptide, fasting glucose and insulin, post-load glucose lipids, HMW-adiponectin and blood pressure (the latter was assessed in each trimester of gestation). At birth, newborns and placentas were weighed.
FASN
expression was also able to be assessed in 80 placentas. Higher circulating FASN was associated with lower systolic blood pressure (SBP), with a more favourable metabolic phenotype (lower fasting glucose and insulin, post load glucose, HbAc1, HOMA-IR and C-peptide), and with lower placental and birth weight (all p |
| doi_str_mv | 10.1038/srep24167 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4835700</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1898677811</sourcerecordid><originalsourceid>FETCH-LOGICAL-c480t-6ac626dc4b2d5b2c98803372760ad9412d5b45f68117f74010806ac10ec726f3</originalsourceid><addsrcrecordid>eNplkt-L1DAQx4Mo3nHeg_-ABHxRcTVJ0yT1QTgWT4UDQe89pOl0N0eb1CT12Af_d1N3XVYNhPyYz3wnkxmEnlLyhpJKvU0RJsapkA_QOSO8XrGKsYcn-zN0mdIdKaNmDafNY3TGJGkIa9Q5-rl20c6Dyc5v8LXJeYevrOvwt53PW5MAO4-nCBtvfMb3YQT_Dn-FhQ8-bd2Ec8DtEEK3UCnNEV7j0WSI3gx4hGzaMLg0YuM77OG-DbHomWiKCWJ6gh71ZkhweVgv0O31h9v1p9XNl4-f11c3K8sVySthrGCis7xlXd0y2yhFqkoyKYjpSkrLLa97oSiVveSEEkWKDyVgJRN9dYHe72WnuR2hs-BzNIOeohtN3OlgnP7b4t1Wb8IPzVVVS0KKAN0L2DRbHcFCtCb_djwelsmIZJqpSglefF4cgsbwfYaU9eiShWEwHsKcNJWqkJTIRf75P-hdmJcfLJRqlJCyZFaol4dHxJBK1ftjApTopRX0sRUK--w04yP5p_AFeLUHUjH5DcSTkP-p_QKxVr7R</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1898677811</pqid></control><display><type>article</type><title>Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters</title><source>MEDLINE</source><source>Nature Free</source><source>DOAJ Directory of Open Access Journals</source><source>Recercat</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature OA Free Journals</source><creator>Carreras-Badosa, Gemma ; Prats-Puig, Anna ; Puig, Teresa ; Vázquez-Ruíz, Montserrat ; Bruel, Monserrat ; Mendoza, Ericka ; de Zegher, Francis ; Ibáñez, Lourdes ; López-Bermejo, Abel ; Bassols, Judit</creator><creatorcontrib>Carreras-Badosa, Gemma ; Prats-Puig, Anna ; Puig, Teresa ; Vázquez-Ruíz, Montserrat ; Bruel, Monserrat ; Mendoza, Ericka ; de Zegher, Francis ; Ibáñez, Lourdes ; López-Bermejo, Abel ; Bassols, Judit</creatorcontrib><description>The enzyme FASN (fatty acid synthase) is potentially related with hypertension and metabolic dysfunction.
FASN
is highly expressed in the human placenta. We aimed to investigate the relationship circulating FASN has with blood pressure, maternal metabolism and newborn parameters in healthy pregnant women. Circulating FASN was assessed in 115 asymptomatic pregnant women in the second trimester of gestation along with C-peptide, fasting glucose and insulin, post-load glucose lipids, HMW-adiponectin and blood pressure (the latter was assessed in each trimester of gestation). At birth, newborns and placentas were weighed.
FASN
expression was also able to be assessed in 80 placentas. Higher circulating FASN was associated with lower systolic blood pressure (SBP), with a more favourable metabolic phenotype (lower fasting glucose and insulin, post load glucose, HbAc1, HOMA-IR and C-peptide), and with lower placental and birth weight (all p < 0.05 to p < 0.001). Placental
FASN
expression related positively to circulating FASN (p < 0.005) and negatively to placental weight (p < 0.05). Our observations suggest a physiological role of placental FASN in human pregnancy. Future studies will clarify whether circulating FASN of placental origin does actually regulate placental and fetal growth, and (thereby) has a favourable influence on the pregnant mother’s insulin sensitivity and blood pressure.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/srep24167</identifier><identifier>PMID: 27090298</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>38/77 ; 692/163/2743/2037 ; 692/308/3187 ; 82 ; Adiponectin ; Adult ; Birth weight ; Blood pressure ; Blood Pressure - genetics ; Complicacions en l'embaràs ; Complications of pregnancy ; Embaràs ; Fasting ; Fatty Acid Synthases - biosynthesis ; Fatty Acid Synthases - blood ; Fatty Acid Synthases - genetics ; Fatty acids ; Fatty-acid synthase ; Female ; Fetuses ; Gene Expression Regulation, Enzymologic ; Gestation ; Glucose ; Glucose - metabolism ; Humanities and Social Sciences ; Humans ; Hypertension ; Hypertension - blood ; Hypertension - enzymology ; Hypertension - genetics ; Hypertension - pathology ; Infant, Newborn ; Insulin ; Insulin - metabolism ; Insulin Resistance - genetics ; Lipid Metabolism - genetics ; Lipids ; Metabolism ; multidisciplinary ; Neonates ; Placenta ; Placenta - enzymology ; Pregnancy ; Science ; Science (multidisciplinary) ; Àcids grassos</subject><ispartof>Scientific reports, 2016-04, Vol.6 (1), p.24167-24167, Article 24167</ispartof><rights>The Author(s) 2016</rights><rights>Copyright Nature Publishing Group Apr 2016</rights><rights>cc-by (c) Carreras-Badosa, Gemma et al., 2016 info:eu-repo/semantics/openAccess <a href="http://creativecommons.org/licenses/by/3.0/es">http://creativecommons.org/licenses/by/3.0/es</a></rights><rights>Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c480t-6ac626dc4b2d5b2c98803372760ad9412d5b45f68117f74010806ac10ec726f3</citedby><cites>FETCH-LOGICAL-c480t-6ac626dc4b2d5b2c98803372760ad9412d5b45f68117f74010806ac10ec726f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835700/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835700/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,26951,27901,27902,41096,42165,51551,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27090298$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carreras-Badosa, Gemma</creatorcontrib><creatorcontrib>Prats-Puig, Anna</creatorcontrib><creatorcontrib>Puig, Teresa</creatorcontrib><creatorcontrib>Vázquez-Ruíz, Montserrat</creatorcontrib><creatorcontrib>Bruel, Monserrat</creatorcontrib><creatorcontrib>Mendoza, Ericka</creatorcontrib><creatorcontrib>de Zegher, Francis</creatorcontrib><creatorcontrib>Ibáñez, Lourdes</creatorcontrib><creatorcontrib>López-Bermejo, Abel</creatorcontrib><creatorcontrib>Bassols, Judit</creatorcontrib><title>Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>The enzyme FASN (fatty acid synthase) is potentially related with hypertension and metabolic dysfunction.
FASN
is highly expressed in the human placenta. We aimed to investigate the relationship circulating FASN has with blood pressure, maternal metabolism and newborn parameters in healthy pregnant women. Circulating FASN was assessed in 115 asymptomatic pregnant women in the second trimester of gestation along with C-peptide, fasting glucose and insulin, post-load glucose lipids, HMW-adiponectin and blood pressure (the latter was assessed in each trimester of gestation). At birth, newborns and placentas were weighed.
FASN
expression was also able to be assessed in 80 placentas. Higher circulating FASN was associated with lower systolic blood pressure (SBP), with a more favourable metabolic phenotype (lower fasting glucose and insulin, post load glucose, HbAc1, HOMA-IR and C-peptide), and with lower placental and birth weight (all p < 0.05 to p < 0.001). Placental
FASN
expression related positively to circulating FASN (p < 0.005) and negatively to placental weight (p < 0.05). Our observations suggest a physiological role of placental FASN in human pregnancy. Future studies will clarify whether circulating FASN of placental origin does actually regulate placental and fetal growth, and (thereby) has a favourable influence on the pregnant mother’s insulin sensitivity and blood pressure.</description><subject>38/77</subject><subject>692/163/2743/2037</subject><subject>692/308/3187</subject><subject>82</subject><subject>Adiponectin</subject><subject>Adult</subject><subject>Birth weight</subject><subject>Blood pressure</subject><subject>Blood Pressure - genetics</subject><subject>Complicacions en l'embaràs</subject><subject>Complications of pregnancy</subject><subject>Embaràs</subject><subject>Fasting</subject><subject>Fatty Acid Synthases - biosynthesis</subject><subject>Fatty Acid Synthases - blood</subject><subject>Fatty Acid Synthases - genetics</subject><subject>Fatty acids</subject><subject>Fatty-acid synthase</subject><subject>Female</subject><subject>Fetuses</subject><subject>Gene Expression Regulation, Enzymologic</subject><subject>Gestation</subject><subject>Glucose</subject><subject>Glucose - metabolism</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension - blood</subject><subject>Hypertension - enzymology</subject><subject>Hypertension - genetics</subject><subject>Hypertension - pathology</subject><subject>Infant, Newborn</subject><subject>Insulin</subject><subject>Insulin - metabolism</subject><subject>Insulin Resistance - genetics</subject><subject>Lipid Metabolism - genetics</subject><subject>Lipids</subject><subject>Metabolism</subject><subject>multidisciplinary</subject><subject>Neonates</subject><subject>Placenta</subject><subject>Placenta - enzymology</subject><subject>Pregnancy</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Àcids grassos</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>XX2</sourceid><recordid>eNplkt-L1DAQx4Mo3nHeg_-ABHxRcTVJ0yT1QTgWT4UDQe89pOl0N0eb1CT12Af_d1N3XVYNhPyYz3wnkxmEnlLyhpJKvU0RJsapkA_QOSO8XrGKsYcn-zN0mdIdKaNmDafNY3TGJGkIa9Q5-rl20c6Dyc5v8LXJeYevrOvwt53PW5MAO4-nCBtvfMb3YQT_Dn-FhQ8-bd2Ec8DtEEK3UCnNEV7j0WSI3gx4hGzaMLg0YuM77OG-DbHomWiKCWJ6gh71ZkhweVgv0O31h9v1p9XNl4-f11c3K8sVySthrGCis7xlXd0y2yhFqkoyKYjpSkrLLa97oSiVveSEEkWKDyVgJRN9dYHe72WnuR2hs-BzNIOeohtN3OlgnP7b4t1Wb8IPzVVVS0KKAN0L2DRbHcFCtCb_djwelsmIZJqpSglefF4cgsbwfYaU9eiShWEwHsKcNJWqkJTIRf75P-hdmJcfLJRqlJCyZFaol4dHxJBK1ftjApTopRX0sRUK--w04yP5p_AFeLUHUjH5DcSTkP-p_QKxVr7R</recordid><startdate>20160419</startdate><enddate>20160419</enddate><creator>Carreras-Badosa, Gemma</creator><creator>Prats-Puig, Anna</creator><creator>Puig, Teresa</creator><creator>Vázquez-Ruíz, Montserrat</creator><creator>Bruel, Monserrat</creator><creator>Mendoza, Ericka</creator><creator>de Zegher, Francis</creator><creator>Ibáñez, Lourdes</creator><creator>López-Bermejo, Abel</creator><creator>Bassols, Judit</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>XX2</scope><scope>5PM</scope></search><sort><creationdate>20160419</creationdate><title>Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters</title><author>Carreras-Badosa, Gemma ; Prats-Puig, Anna ; Puig, Teresa ; Vázquez-Ruíz, Montserrat ; Bruel, Monserrat ; Mendoza, Ericka ; de Zegher, Francis ; Ibáñez, Lourdes ; López-Bermejo, Abel ; Bassols, Judit</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-6ac626dc4b2d5b2c98803372760ad9412d5b45f68117f74010806ac10ec726f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>38/77</topic><topic>692/163/2743/2037</topic><topic>692/308/3187</topic><topic>82</topic><topic>Adiponectin</topic><topic>Adult</topic><topic>Birth weight</topic><topic>Blood pressure</topic><topic>Blood Pressure - genetics</topic><topic>Complicacions en l'embaràs</topic><topic>Complications of pregnancy</topic><topic>Embaràs</topic><topic>Fasting</topic><topic>Fatty Acid Synthases - biosynthesis</topic><topic>Fatty Acid Synthases - blood</topic><topic>Fatty Acid Synthases - genetics</topic><topic>Fatty acids</topic><topic>Fatty-acid synthase</topic><topic>Female</topic><topic>Fetuses</topic><topic>Gene Expression Regulation, Enzymologic</topic><topic>Gestation</topic><topic>Glucose</topic><topic>Glucose - metabolism</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypertension - blood</topic><topic>Hypertension - enzymology</topic><topic>Hypertension - genetics</topic><topic>Hypertension - pathology</topic><topic>Infant, Newborn</topic><topic>Insulin</topic><topic>Insulin - metabolism</topic><topic>Insulin Resistance - genetics</topic><topic>Lipid Metabolism - genetics</topic><topic>Lipids</topic><topic>Metabolism</topic><topic>multidisciplinary</topic><topic>Neonates</topic><topic>Placenta</topic><topic>Placenta - enzymology</topic><topic>Pregnancy</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Àcids grassos</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carreras-Badosa, Gemma</creatorcontrib><creatorcontrib>Prats-Puig, Anna</creatorcontrib><creatorcontrib>Puig, Teresa</creatorcontrib><creatorcontrib>Vázquez-Ruíz, Montserrat</creatorcontrib><creatorcontrib>Bruel, Monserrat</creatorcontrib><creatorcontrib>Mendoza, Ericka</creatorcontrib><creatorcontrib>de Zegher, Francis</creatorcontrib><creatorcontrib>Ibáñez, Lourdes</creatorcontrib><creatorcontrib>López-Bermejo, Abel</creatorcontrib><creatorcontrib>Bassols, Judit</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Recercat</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carreras-Badosa, Gemma</au><au>Prats-Puig, Anna</au><au>Puig, Teresa</au><au>Vázquez-Ruíz, Montserrat</au><au>Bruel, Monserrat</au><au>Mendoza, Ericka</au><au>de Zegher, Francis</au><au>Ibáñez, Lourdes</au><au>López-Bermejo, Abel</au><au>Bassols, Judit</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2016-04-19</date><risdate>2016</risdate><volume>6</volume><issue>1</issue><spage>24167</spage><epage>24167</epage><pages>24167-24167</pages><artnum>24167</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>The enzyme FASN (fatty acid synthase) is potentially related with hypertension and metabolic dysfunction.
FASN
is highly expressed in the human placenta. We aimed to investigate the relationship circulating FASN has with blood pressure, maternal metabolism and newborn parameters in healthy pregnant women. Circulating FASN was assessed in 115 asymptomatic pregnant women in the second trimester of gestation along with C-peptide, fasting glucose and insulin, post-load glucose lipids, HMW-adiponectin and blood pressure (the latter was assessed in each trimester of gestation). At birth, newborns and placentas were weighed.
FASN
expression was also able to be assessed in 80 placentas. Higher circulating FASN was associated with lower systolic blood pressure (SBP), with a more favourable metabolic phenotype (lower fasting glucose and insulin, post load glucose, HbAc1, HOMA-IR and C-peptide), and with lower placental and birth weight (all p < 0.05 to p < 0.001). Placental
FASN
expression related positively to circulating FASN (p < 0.005) and negatively to placental weight (p < 0.05). Our observations suggest a physiological role of placental FASN in human pregnancy. Future studies will clarify whether circulating FASN of placental origin does actually regulate placental and fetal growth, and (thereby) has a favourable influence on the pregnant mother’s insulin sensitivity and blood pressure.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>27090298</pmid><doi>10.1038/srep24167</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2045-2322 |
| ispartof | Scientific reports, 2016-04, Vol.6 (1), p.24167-24167, Article 24167 |
| issn | 2045-2322 2045-2322 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4835700 |
| source | MEDLINE; Nature Free; DOAJ Directory of Open Access Journals; Recercat; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry; Springer Nature OA Free Journals |
| subjects | 38/77 692/163/2743/2037 692/308/3187 82 Adiponectin Adult Birth weight Blood pressure Blood Pressure - genetics Complicacions en l'embaràs Complications of pregnancy Embaràs Fasting Fatty Acid Synthases - biosynthesis Fatty Acid Synthases - blood Fatty Acid Synthases - genetics Fatty acids Fatty-acid synthase Female Fetuses Gene Expression Regulation, Enzymologic Gestation Glucose Glucose - metabolism Humanities and Social Sciences Humans Hypertension Hypertension - blood Hypertension - enzymology Hypertension - genetics Hypertension - pathology Infant, Newborn Insulin Insulin - metabolism Insulin Resistance - genetics Lipid Metabolism - genetics Lipids Metabolism multidisciplinary Neonates Placenta Placenta - enzymology Pregnancy Science Science (multidisciplinary) Àcids grassos |
| title | Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T06%3A00%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Circulating%20Fatty%20Acid%20Synthase%20in%20pregnant%20women:%20Relationship%20to%20blood%20pressure,%20maternal%20metabolism%20and%20newborn%20parameters&rft.jtitle=Scientific%20reports&rft.au=Carreras-Badosa,%20Gemma&rft.date=2016-04-19&rft.volume=6&rft.issue=1&rft.spage=24167&rft.epage=24167&rft.pages=24167-24167&rft.artnum=24167&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/srep24167&rft_dat=%3Cproquest_pubme%3E1898677811%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1898677811&rft_id=info:pmid/27090298&rfr_iscdi=true |