Prenatal Alcohol Exposure Increases Vulnerability to Stress and Anxiety-Like Disorders in Adulthood

Children and adults with fetal alcohol spectrum disorder (FASD) have elevated rates of depression and anxiety disorders compared to control populations. The effects of prenatal alcohol exposure (PAE) on anxiety, locomotor activity, and hormonal reactivity in male and female rats tested on the elevat...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2008-11, Vol.1144 (1), p.154-175
Hauptverfasser:	Hellemans, Kim G.C., Verma, Pamela, Yoon, Esther, Yu, Wayne, Weinberg, Joanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anxiety Anxiety Disorders - etiology Anxiety Disorders - metabolism Anxiety Disorders - pathology behavior chronic mild stress Corticosterone - blood early adversity elevated plus maze Ethanol - pharmacology Ethanol - toxicity Female fetal programming HPA axis HPG axis Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - metabolism Male Maze Learning Pituitary-Adrenal System - drug effects Pituitary-Adrenal System - metabolism Pregnancy prenatal alcohol exposure Prenatal Exposure Delayed Effects - etiology Prenatal Exposure Delayed Effects - metabolism Rats Rats, Sprague-Dawley sex differences Sprague-Dawley Stress, Psychological - etiology Stress, Psychological - metabolism Stress, Psychological - pathology
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