Fibroblast growth factor receptor‐1 protein expression is associated with prognosis in estrogen receptor‐positive/human epidermal growth factor receptor‐2‐negative primary breast cancer

Recently, research into the development of new targeted therapies has focused on specific genetic alterations to create advanced, more personalized treatment. One of the target genes, fibroblast growth factor receptor‐1 (FGFR1), has been reported to be amplified in estrogen receptor (ER)‐positive su...

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Veröffentlicht in:	Cancer science 2016-04, Vol.107 (4), p.491-498
Hauptverfasser:	Tomiguchi, Mai, Yamamoto, Yutaka, Yamamoto‐Ibusuki, Mutsuko, Goto‐Yamaguchi, Lisa, Fujiki, Yoshitaka, Fujiwara, Saori, Sueta, Aiko, Hayashi, Mitsuhiro, Takeshita, Takashi, Inao, Touko, Iwase, Hirotaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarker Biomarkers, Tumor - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Copy number Deoxyribonucleic acid DNA Epidermal growth factor ErbB-2 protein ER‐positive/HER2‐negative Estrogen receptors Female Fibroblast growth factor receptor 1 Fibroblast growth factor receptors Fibroblasts Gene amplification Gene Dosage - genetics Gene expression Genomics Humans Invasiveness Kinases Medical prognosis Menopause Middle Aged Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Original Patients Prognosis Protein expression Proteins Receptor, ErbB-2 - genetics Receptor, Fibroblast Growth Factor, Type 1 - biosynthesis Receptor, Fibroblast Growth Factor, Type 1 - genetics Receptors, Estrogen - genetics RNA, Messenger - biosynthesis Studies Thermal cycling Transcription
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