Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells

Although oligodendrocytes constitute a significant proportion of cells in the central nervous system (CNS), little is known about their intermediary metabolism. We have, therefore, characterized metabolic functions of primary oligodendrocyte precursor cell cultures at late stages of differentiation...

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Veröffentlicht in:	Glia 2016-01, Vol.64 (1), p.21-34
Hauptverfasser:	Amaral, Ana I., Hadera, Mussie G., Tavares, Joana M., Kotter, Mark R. N., Sonnewald, Ursula
Format:	Artikel
Sprache:	eng
Schlagworte:	13C acetate Acetates - metabolism Acetyl Coenzyme A - metabolism Animals Carbon Radioisotopes Cells, Cultured Citric Acid Cycle - physiology Cytosol - metabolism energy metabolism Glucose Glucose - metabolism glycolysis Labeling Lactic Acid - metabolism Malates - metabolism Metabolism Metabolites mitochondria Mitochondria - metabolism Neural Stem Cells - metabolism oligodendroglia Oligodendroglia - metabolism Oxaloacetic Acid - metabolism Pentose Phosphate Pathway - physiology Phosphoenolpyruvate - metabolism pyruvate carboxylation Pyruvic Acid - metabolism Radiopharmaceuticals Rats, Sprague-Dawley
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