A prefoldin-associated WD-repeat protein (WDR92) is required for the correct architectural assembly of motile cilia

WDR92 is a highly conserved WD-repeat protein that has been proposed to be involved in apoptosis and also to be part of a prefoldin-like cochaperone complex. We found that WDR92 has a phylogenetic signature that is generally compatible with it playing a role in the assembly or function of specifical...

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Veröffentlicht in:	Molecular biology of the cell 2016-04, Vol.27 (8), p.1204-1209
Hauptverfasser:	Patel-King, Ramila S, King, Stephen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axoneme - metabolism Brief Reports Cilia - genetics Cilia - metabolism Cilia - ultrastructure Gene Knockdown Techniques Helminth Proteins - chemistry Helminth Proteins - genetics Helminth Proteins - metabolism Microscopy, Electron, Transmission Molecular Chaperones - metabolism Multiprotein Complexes - metabolism Phylogeny Planarians - cytology Planarians - genetics Planarians - metabolism RNA Interference
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