Microstructural changes to the brain of mice after methamphetamine exposure as identified with diffusion tensor imaging

Abstract Methamphetamine (METH) is an addictive psychostimulant inducing neurotoxicity. Human magnetic resonance imaging and diffusion tensor imaging (DTI) of METH-dependent participants find various structural abnormities. Animal studies demonstrate immunohistochemical changes in multiple cellular...

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Veröffentlicht in:	Psychiatry research. Neuroimaging 2016-03, Vol.249, p.27-37
Hauptverfasser:	McKenna, Benjamin S, Brown, Gregory G, Archibald, Sarah, Scadeng, Miriam, Bussell, Robert, Kesby, James P, Markou, Athina, Soontornniyomkij, Virawudh, Achim, Cristian, Semenova, Svetlana, The Translational Methamphetamine AIDS Research Center (TMARC) Group
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anisotropy Brain - diagnostic imaging Brain - drug effects Brain - pathology Central Nervous System Stimulants - adverse effects Corpus Callosum - diagnostic imaging Corpus Callosum - drug effects Corpus Callosum - pathology Diffusion tensor imaging Diffusion Tensor Imaging - methods Fractional anisotropy Internal Capsule - diagnostic imaging Internal Capsule - drug effects Internal Capsule - pathology Magnetic resonance imaging Male Mean diffusivity Methamphetamine Methamphetamine - adverse effects Mice Mice, Inbred C57BL Mouse Psychiatry Radiology Thalamus - diagnostic imaging Thalamus - drug effects Thalamus - pathology
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