Digoxin reduces atherosclerosis in apolipoprotein E‐deficient mice

Background and Purpose Numerous in vitro studies have suggested that digoxin suppresses inflammation and alters lipid metabolism. However, the effect of dioxin on atherosclerosis is poorly understood. The present study was conducted to determine whether digoxin affects the development of atheroscler...

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Veröffentlicht in:	British journal of pharmacology 2016-05, Vol.173 (9), p.1517-1528
Hauptverfasser:	Shi, Huairui, Mao, Xiaobo, Zhong, Yucheng, Liu, Yuzhou, Zhao, Xiaoqi, Yu, Kunwu, Zhu, Ruirui, Wei, Yuzhen, Zhu, Jianghao, Sun, Haitao, Mao, Yi, Zeng, Qiutang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoproteins E - deficiency Apolipoproteins E - metabolism Atherosclerosis - drug therapy Atherosclerosis - immunology Atherosclerosis - metabolism Digoxin - blood Digoxin - metabolism Digoxin - pharmacology Dose-Response Relationship, Drug Inflammation - drug therapy Inflammation - immunology Interleukin-17 - immunology Mice Mice, Inbred C57BL Mice, Knockout Nuclear Receptor Subfamily 1, Group F, Member 3 - antagonists & inhibitors Research Paper Research Papers
Online-Zugang:	Volltext
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