Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes1

The 5-lipoxygenase product 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is the most powerful human eosinophil chemoattractant among lipid mediators and could play a major pathophysiological role in eosinophilic diseases such as asthma. Its actions are mediated by the OXE receptor, orthologs of...

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Veröffentlicht in:Biochemical pharmacology 2015-05, Vol.96 (3), p.247-255
Hauptverfasser: Cossette, Chantal, Gravel, Sylvie, Reddy, Chintam Nagendra, Gore, Vivek, Chourey, Shishir, Ye, Qiuji, Snyder, Nathaniel W., Mesaros, Clementina A., Blair, Ian A., Lavoie, Jean-Pierre, Reinero, Carol R., Rokach, Joshua, Powell, William S.
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Sprache:eng
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