Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis

Inhibitor of DNA binding 1 (Id1) is a nuclear protein containing a basic helix-loop-helix (bHLH) domain that regulates cell growth by selective binding and prevention of gene transcription. Sources of Id1 production in rheumatoid arthritis synovial tissue (RA ST) and its range of functional effects...

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Veröffentlicht in:	Arthritis research & therapy 2016-04, Vol.18 (87), p.87-87, Article 87
Hauptverfasser:	Edhayan, Gautam, Ohara, Ray A, Stinson, W Alex, Amin, M Asif, Isozaki, Takeo, Ha, Christine M, Haines, 3rd, G Kenneth, Morgan, Rachel, Campbell, Phillip L, Arbab, Ali S, Friday, Sean C, Fox, David A, Ruth, Jeffrey H
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Arthritis Arthritis, Experimental - metabolism Arthritis, Experimental - pathology Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Blotting, Western Cells, Cultured DNA-ligand interactions Enzyme-Linked Immunosorbent Assay Fibroblasts - metabolism Fluorescent Antibody Technique Humans Immunohistochemistry Inflammation - metabolism Inflammation - pathology Inhibitor of Differentiation Protein 1 - metabolism Mice Mice, Inbred C57BL Mice, SCID Polymerase chain reaction Real-Time Polymerase Chain Reaction Rheumatoid arthritis Synovial Membrane - metabolism
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