Overexpression of Oct4 in porcine ovarian stem/stromal cells enhances differentiation of oocyte-like cells in vitro and ovarian follicular formation in vivo

Recent findings have revealed that the female gonad may have regenerative activity with having germ line stem cells in juveniles and adults. Application of these germ line stem cells could be an alternative therapy for reproductive disorders in regenerative medicine. To enhance the potency of differ...

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Veröffentlicht in:	Journal of ovarian research 2016-04, Vol.9 (24), p.24-24, Article 24
Hauptverfasser:	Lee, Yeon-Mi, Kim, Tae-Ho, Lee, Jeong-Hyeon, Lee, Won-Jae, Jeon, Ryoung-Hoon, Jang, Si-Jung, Ock, Sun-A, Lee, Sung-Lim, Park, Bong-Wook, Rho, Gyu-Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biomarkers - metabolism Cell Differentiation Cell Proliferation Cell Shape Cells, Cultured Estradiol Estradiol - blood Female Follicle Stimulating Hormone - blood Gene Expression Infertility, Female - blood Infertility, Female - therapy Mice, Inbred BALB C Mice, Nude Octamer Transcription Factor-3 - genetics Octamer Transcription Factor-3 - metabolism Oocytes - physiology Ovarian Follicle - pathology Physiological aspects Stem Cell Transplantation Stem cells Stem Cells - physiology Sus scrofa Transplantation
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