Ribonucleoprotein particles of bacterial small non-coding RNA IsrA (IS61 or McaS) and its interaction with RNA polymerase core may link transcription to mRNA fate

Coupled transcription and translation in bacteria are tightly regulated. Some small RNAs (sRNAs) control aspects of this coupling by modifying ribosome access or inducing degradation of the message. Here, we show that sRNA IsrA (IS61 or McaS) specifically associates with core enzyme of RNAP in vivo...

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Veröffentlicht in:Nucleic acids research 2016-04, Vol.44 (6), p.2577-2592
Hauptverfasser: van Nues, Rob W, Castro-Roa, Daniel, Yuzenkova, Yulia, Zenkin, Nikolay
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Sprache:eng
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