Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study
Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadn...
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| Veröffentlicht in: | BMC psychiatry 2016-04, Vol.16 (94), p.94-94, Article 94 |
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| creator | Moreno-Küstner, Berta Jones, Rebeca Švab, Igor Maaroos, Heidi Xavier, Miguel Geerlings, Mirjam Torres-González, Francisco Nazareth, Irwin Motrico-Martínez, Emma Montón-Franco, Carmen Gil-de-Gómez, María José Sánchez-Celaya, Marta Díaz-Barreiros, Miguel Ángel Vicens-Caldentey, Catalina King, Michael |
| description | Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia.
Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months.
1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months.
Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression. |
| doi_str_mv | 10.1186/s12888-016-0775-z |
| format | Article |
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Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months.
1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months.
Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.</description><identifier>ISSN: 1471-244X</identifier><identifier>EISSN: 1471-244X</identifier><identifier>DOI: 10.1186/s12888-016-0775-z</identifier><identifier>PMID: 27053286</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Analysis ; Anhedonia ; Care and treatment ; Cohort Studies ; Complications and side effects ; Depressive Disorder, Major - epidemiology ; Depressive Disorder, Major - psychology ; Europe - epidemiology ; Family physicians ; Female ; Humans ; Male ; Mental depression ; Mental disorders ; Middle Aged ; Primary care ; Primary Health Care ; Prospective Studies ; Psychiatry ; Suicidal behavior ; Suicide - psychology ; Suicide - statistics & numerical data ; Suicides & suicide attempts</subject><ispartof>BMC psychiatry, 2016-04, Vol.16 (94), p.94-94, Article 94</ispartof><rights>COPYRIGHT 2016 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2016</rights><rights>Moreno-Küstner et al. 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-aacd7b4f8dbfffe0b5167ed96bd3a36c8e0d21d2b451aa78ad7354ae0106e5e13</citedby><cites>FETCH-LOGICAL-c494t-aacd7b4f8dbfffe0b5167ed96bd3a36c8e0d21d2b451aa78ad7354ae0106e5e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823872/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823872/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27053286$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moreno-Küstner, Berta</creatorcontrib><creatorcontrib>Jones, Rebeca</creatorcontrib><creatorcontrib>Švab, Igor</creatorcontrib><creatorcontrib>Maaroos, Heidi</creatorcontrib><creatorcontrib>Xavier, Miguel</creatorcontrib><creatorcontrib>Geerlings, Mirjam</creatorcontrib><creatorcontrib>Torres-González, Francisco</creatorcontrib><creatorcontrib>Nazareth, Irwin</creatorcontrib><creatorcontrib>Motrico-Martínez, Emma</creatorcontrib><creatorcontrib>Montón-Franco, Carmen</creatorcontrib><creatorcontrib>Gil-de-Gómez, María José</creatorcontrib><creatorcontrib>Sánchez-Celaya, Marta</creatorcontrib><creatorcontrib>Díaz-Barreiros, Miguel Ángel</creatorcontrib><creatorcontrib>Vicens-Caldentey, Catalina</creatorcontrib><creatorcontrib>King, Michael</creatorcontrib><title>Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study</title><title>BMC psychiatry</title><addtitle>BMC Psychiatry</addtitle><description>Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia.
Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months.
1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months.
Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.</description><subject>Analysis</subject><subject>Anhedonia</subject><subject>Care and treatment</subject><subject>Cohort Studies</subject><subject>Complications and side effects</subject><subject>Depressive Disorder, Major - epidemiology</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Europe - epidemiology</subject><subject>Family physicians</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Middle Aged</subject><subject>Primary care</subject><subject>Primary Health Care</subject><subject>Prospective Studies</subject><subject>Psychiatry</subject><subject>Suicidal behavior</subject><subject>Suicide - psychology</subject><subject>Suicide - statistics & numerical data</subject><subject>Suicides & suicide attempts</subject><issn>1471-244X</issn><issn>1471-244X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNptUk1v1DAQjRCIfsAP4IIsceklxeM4scMBqapKQarEAZC4WRN70nWVtUOctNr-erzapbQIWZbHnveeZ0avKN4APwXQzfsEQmtdcmhKrlRd3j8rDkEqKIWUP58_ig-Ko5RuOAela3hZHAjF60ro5rDw3xZvvcPBzxvmAxsnv8ZpwyxOxEacPYU5sbtVzBlK-cLu_LxiCV2glBgGl_eKXAwePzDMqJhGsrO_JXaxTHEkDCzNi9u8Kl70OCR6vT-Pix-fLr6ffy6vvl5-OT-7Kq1s5VwiWqc62WvX9X1PvKuhUeTapnMVVo3VxJ0AJzpZA6LS6FRVSyQOvKGaoDouPu50x6Vbk7O55gkHs2_MRPTmaSb4lbmOt0ZqUWklssDJXmCKvxZKs1n7ZGkYMFBckgGlWq0bJXmGvvsHehOXKeT2MqpVDWgh2r-oaxzI-NDH_K_dipozKbUCoeS27tP_oPJytPY2Bup9fn9CgB3B5pmnifqHHoGbrT_Mzh8m-8Ns_WHuM-ft4-E8MP4YovoN0ZO4mw</recordid><startdate>20160406</startdate><enddate>20160406</enddate><creator>Moreno-Küstner, Berta</creator><creator>Jones, Rebeca</creator><creator>Švab, Igor</creator><creator>Maaroos, Heidi</creator><creator>Xavier, Miguel</creator><creator>Geerlings, Mirjam</creator><creator>Torres-González, Francisco</creator><creator>Nazareth, Irwin</creator><creator>Motrico-Martínez, Emma</creator><creator>Montón-Franco, Carmen</creator><creator>Gil-de-Gómez, María José</creator><creator>Sánchez-Celaya, Marta</creator><creator>Díaz-Barreiros, Miguel Ángel</creator><creator>Vicens-Caldentey, Catalina</creator><creator>King, Michael</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160406</creationdate><title>Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study</title><author>Moreno-Küstner, Berta ; Jones, Rebeca ; Švab, Igor ; Maaroos, Heidi ; Xavier, Miguel ; Geerlings, Mirjam ; Torres-González, Francisco ; Nazareth, Irwin ; Motrico-Martínez, Emma ; Montón-Franco, Carmen ; Gil-de-Gómez, María José ; Sánchez-Celaya, Marta ; Díaz-Barreiros, Miguel Ángel ; Vicens-Caldentey, Catalina ; King, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-aacd7b4f8dbfffe0b5167ed96bd3a36c8e0d21d2b451aa78ad7354ae0106e5e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Analysis</topic><topic>Anhedonia</topic><topic>Care and treatment</topic><topic>Cohort Studies</topic><topic>Complications and side effects</topic><topic>Depressive Disorder, Major - epidemiology</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Europe - epidemiology</topic><topic>Family physicians</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Mental depression</topic><topic>Mental disorders</topic><topic>Middle Aged</topic><topic>Primary care</topic><topic>Primary Health Care</topic><topic>Prospective Studies</topic><topic>Psychiatry</topic><topic>Suicidal behavior</topic><topic>Suicide - psychology</topic><topic>Suicide - statistics & numerical data</topic><topic>Suicides & suicide attempts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moreno-Küstner, Berta</creatorcontrib><creatorcontrib>Jones, Rebeca</creatorcontrib><creatorcontrib>Švab, Igor</creatorcontrib><creatorcontrib>Maaroos, Heidi</creatorcontrib><creatorcontrib>Xavier, Miguel</creatorcontrib><creatorcontrib>Geerlings, Mirjam</creatorcontrib><creatorcontrib>Torres-González, Francisco</creatorcontrib><creatorcontrib>Nazareth, Irwin</creatorcontrib><creatorcontrib>Motrico-Martínez, Emma</creatorcontrib><creatorcontrib>Montón-Franco, Carmen</creatorcontrib><creatorcontrib>Gil-de-Gómez, María José</creatorcontrib><creatorcontrib>Sánchez-Celaya, Marta</creatorcontrib><creatorcontrib>Díaz-Barreiros, Miguel Ángel</creatorcontrib><creatorcontrib>Vicens-Caldentey, Catalina</creatorcontrib><creatorcontrib>King, Michael</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moreno-Küstner, Berta</au><au>Jones, Rebeca</au><au>Švab, Igor</au><au>Maaroos, Heidi</au><au>Xavier, Miguel</au><au>Geerlings, Mirjam</au><au>Torres-González, Francisco</au><au>Nazareth, Irwin</au><au>Motrico-Martínez, Emma</au><au>Montón-Franco, Carmen</au><au>Gil-de-Gómez, María José</au><au>Sánchez-Celaya, Marta</au><au>Díaz-Barreiros, Miguel Ángel</au><au>Vicens-Caldentey, Catalina</au><au>King, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study</atitle><jtitle>BMC psychiatry</jtitle><addtitle>BMC Psychiatry</addtitle><date>2016-04-06</date><risdate>2016</risdate><volume>16</volume><issue>94</issue><spage>94</spage><epage>94</epage><pages>94-94</pages><artnum>94</artnum><issn>1471-244X</issn><eissn>1471-244X</eissn><abstract>Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia.
Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months.
1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months.
Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>27053286</pmid><doi>10.1186/s12888-016-0775-z</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Analysis Anhedonia Care and treatment Cohort Studies Complications and side effects Depressive Disorder, Major - epidemiology Depressive Disorder, Major - psychology Europe - epidemiology Family physicians Female Humans Male Mental depression Mental disorders Middle Aged Primary care Primary Health Care Prospective Studies Psychiatry Suicidal behavior Suicide - psychology Suicide - statistics & numerical data Suicides & suicide attempts |
| title | Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study |
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