Gallic acid induced apoptotic events in HCT-15 colon cancer cells

AIM: To investigate the inhibitory action of diet-derived phenolic compound gallic acid(GA) against HCT-15 colon cancer cells.METHODS: The antiproliferative effect of GA against colon cancer cells was determined by performing thiazolyl blue tetrazolium bromide(MTT) assay. The colony forming ability...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2016-04, Vol.22 (15), p.3952-3961
Hauptverfasser:	Subramanian, Aruna Priyadharshni, Jaganathan, Saravana Kumar, Mandal, Mahitosh, Supriyanto, Eko, Muhamad, Ida Idayu
Format:	Artikel
Sprache:	eng
Schlagworte:	acid Colon Adenocarcinoma - drug therapy Adenocarcinoma - metabolism Adenocarcinoma - ultrastructure Antineoplastic Agents - pharmacology Apoptosis - drug effects Basic Study break cancer Apoptosis Cell Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Colonic Neoplasms - drug therapy Colonic Neoplasms - metabolism Colonic Neoplasms - ultrastructure cycle Reactive Dose-Response Relationship, Drug G1 Phase Cell Cycle Checkpoints - drug effects Gallic Gallic Acid - pharmacology Humans Inhibitory Concentration 50 layer Membrane Potential, Mitochondrial - drug effects Oxidative Stress - drug effects oxygen Reactive Oxygen Species - metabolism species Lipid Time Factors
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