Concise Total Synthesis of Lundurines A–C Enabled by Gold Catalysis and a Homodienyl Retro-Ene/Ene Isomerization

The total synthesis of lundurines A–C has been accomplished in racemic and enantiopure forms in 11–13 and 12–14 steps, respectively, without protection/deprotection of functional groups, by a novel tandem double condensation/Claisen rearrangement, a gold­(I)-catalyzed alkyne hydroarylation, a cyclop...

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Veröffentlicht in:	Journal of the American Chemical Society 2016-03, Vol.138 (11), p.3671-3674
Hauptverfasser:	Kirillova, Mariia S, Muratore, Michael E, Dorel, Ruth, Echavarren, Antonio M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes catalytic activity Communication Condensation enantiomers Extrusion Gold Isomerization Migration nitrogen olefin Olefins Synthesis
Online-Zugang:	Volltext
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