A porcine model of osteosarcoma

We previously produced pigs with a latent oncogenic TP53 mutation. Humans with TP53 germline mutations are predisposed to a wide spectrum of early-onset cancers, predominantly breast, brain, adrenal gland cancer, soft tissue sarcomas and osteosarcomas. Loss of p53 function has been observed in >5...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Oncogenesis (New York, NY) NY), 2016-03, Vol.5 (3), p.e210-e210
Hauptverfasser:	Saalfrank, A, Janssen, K-P, Ravon, M, Flisikowski, K, Eser, S, Steiger, K, Flisikowska, T, Müller-Fliedner, P, Schulze, É, Brönner, C, Gnann, A, Kappe, E, Böhm, B, Schade, B, Certa, U, Saur, D, Esposito, I, Kind, A, Schnieke, A
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1344 631/67/68 Apoptosis Cancer Cell Biology Hogs Human Genetics Internal Medicine Medicine Medicine & Public Health Mutation Oncology Original original-article
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!