Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings
Although for decades there has been controversy regarding the relationship between obesity and coronary artery disease (CAD), it has been assumed that high body mass index (BMI) is a risk factor for CAD. However, the findings of some recent studies were paradoxical. The aim of this study was to find...
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| Veröffentlicht in: | Cardiovascular Journal of Africa 2015-01, Vol.26 (1), p.13-16 |
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| description | Although for decades there has been controversy regarding the relationship between obesity and coronary artery disease (CAD), it has been assumed that high body mass index (BMI) is a risk factor for CAD. However, the findings of some recent studies were paradoxical.
The aim of this study was to find a relationship between high BMI and waist-to-hip ratio (WHR) with severity of CAD.
This study was a cross-sectional, prospective study where 414 patients with suspected coronary artery disease, in whom coronary angiography was performed, were enrolled. The mean ± SD of their ages was 61.2 ± 27.4 years (range 25-84), and 250 (60.4%) were male. Regarding cardiovascular risk factors, 113 (27.3%) patients had a history of diabetes mellitus (DM), 162 (39.1%) had hypercholesterolaemia, 238 (57.4%) had hypertension, 109 (26.3%) were current smokers and 24 (5.8%) had a family history of CAD. The mean ± SD of the patients' BMI was 26.04 ± 4.08 kg/m(2) (range 16-39) and means ± SD of their WHR ranged from 0.951 ± 0.07 to 0.987 ± 0.05. The mean ± SD of the severity of CAD according to the SYNTAX and Duke scores were 17.7 ± 9.6 (range 0-64) and 3.2 ± 1.7 (range 0-12), respectively.
In this study, findings showed a negative correlation between the severity of CAD and BMI, according to both SYNTAX and Duke scores (p ≤ 0.001 and p = 0.001, respectively). However, there was a positive correlation between WHR and severity of CAD, according to the Duke score (p = 0.03).
BMI had a negative correlation with the severity of CAD, but waist-to-hip ratio had a positive correlation with severity of CAD. |
| doi_str_mv | 10.5830/CVJA-2014-054 |
| format | Article |
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The aim of this study was to find a relationship between high BMI and waist-to-hip ratio (WHR) with severity of CAD.
This study was a cross-sectional, prospective study where 414 patients with suspected coronary artery disease, in whom coronary angiography was performed, were enrolled. The mean ± SD of their ages was 61.2 ± 27.4 years (range 25-84), and 250 (60.4%) were male. Regarding cardiovascular risk factors, 113 (27.3%) patients had a history of diabetes mellitus (DM), 162 (39.1%) had hypercholesterolaemia, 238 (57.4%) had hypertension, 109 (26.3%) were current smokers and 24 (5.8%) had a family history of CAD. The mean ± SD of the patients' BMI was 26.04 ± 4.08 kg/m(2) (range 16-39) and means ± SD of their WHR ranged from 0.951 ± 0.07 to 0.987 ± 0.05. The mean ± SD of the severity of CAD according to the SYNTAX and Duke scores were 17.7 ± 9.6 (range 0-64) and 3.2 ± 1.7 (range 0-12), respectively.
In this study, findings showed a negative correlation between the severity of CAD and BMI, according to both SYNTAX and Duke scores (p ≤ 0.001 and p = 0.001, respectively). However, there was a positive correlation between WHR and severity of CAD, according to the Duke score (p = 0.03).
BMI had a negative correlation with the severity of CAD, but waist-to-hip ratio had a positive correlation with severity of CAD.</description><identifier>ISSN: 1995-1892</identifier><identifier>EISSN: 1680-0745</identifier><identifier>DOI: 10.5830/CVJA-2014-054</identifier><identifier>PMID: 25784312</identifier><language>eng</language><publisher>South Africa: Clinics Cardive Publishing</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Cardiovascular Topics ; Comorbidity ; Coronary Angiography ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - epidemiology ; Coronary Artery Disease - prevention & control ; Cross-Sectional Studies ; Female ; Humans ; Iran - epidemiology ; Male ; Middle Aged ; Obesity - diagnosis ; Obesity - epidemiology ; Predictive Value of Tests ; Prevalence ; Prospective Studies ; Protective Factors ; Risk Factors ; Severity of Illness Index ; Waist-Hip Ratio ; Young Adult</subject><ispartof>Cardiovascular Journal of Africa, 2015-01, Vol.26 (1), p.13-16</ispartof><rights>Copyright © 2010 Clinics Cardive Publishing. This work is licensed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2010 Clinics Cardive Publishing 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814759/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814759/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25784312$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Parsa, A F</creatorcontrib><creatorcontrib>Jahanshahi, B</creatorcontrib><title>Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings</title><title>Cardiovascular Journal of Africa</title><addtitle>Cardiovasc J Afr</addtitle><description>Although for decades there has been controversy regarding the relationship between obesity and coronary artery disease (CAD), it has been assumed that high body mass index (BMI) is a risk factor for CAD. However, the findings of some recent studies were paradoxical.
The aim of this study was to find a relationship between high BMI and waist-to-hip ratio (WHR) with severity of CAD.
This study was a cross-sectional, prospective study where 414 patients with suspected coronary artery disease, in whom coronary angiography was performed, were enrolled. The mean ± SD of their ages was 61.2 ± 27.4 years (range 25-84), and 250 (60.4%) were male. Regarding cardiovascular risk factors, 113 (27.3%) patients had a history of diabetes mellitus (DM), 162 (39.1%) had hypercholesterolaemia, 238 (57.4%) had hypertension, 109 (26.3%) were current smokers and 24 (5.8%) had a family history of CAD. The mean ± SD of the patients' BMI was 26.04 ± 4.08 kg/m(2) (range 16-39) and means ± SD of their WHR ranged from 0.951 ± 0.07 to 0.987 ± 0.05. The mean ± SD of the severity of CAD according to the SYNTAX and Duke scores were 17.7 ± 9.6 (range 0-64) and 3.2 ± 1.7 (range 0-12), respectively.
In this study, findings showed a negative correlation between the severity of CAD and BMI, according to both SYNTAX and Duke scores (p ≤ 0.001 and p = 0.001, respectively). However, there was a positive correlation between WHR and severity of CAD, according to the Duke score (p = 0.03).
BMI had a negative correlation with the severity of CAD, but waist-to-hip ratio had a positive correlation with severity of CAD.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body Mass Index</subject><subject>Cardiovascular Topics</subject><subject>Comorbidity</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Coronary Artery Disease - prevention & control</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Iran - epidemiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Obesity - diagnosis</subject><subject>Obesity - epidemiology</subject><subject>Predictive Value of Tests</subject><subject>Prevalence</subject><subject>Prospective Studies</subject><subject>Protective Factors</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Waist-Hip Ratio</subject><subject>Young Adult</subject><issn>1995-1892</issn><issn>1680-0745</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkUtvFDEQhC0EIg84ckWWuHBxsD1-zQUUrSAJigQH4DrqWdtZRzP2YnuT7A_j_-ERCQJOnKqlLn1dpUboBaMn0nT0zerbx1PCKROESvEIHTJlKKFayMdt7ntJmOn5AToq5ZpSzo2WT9EBl9qIjvFD9OOi4LpxOLsJakixbMIWJ4_HZPd4hlJwiNbd4ZpwcTcuh7pf1uuUU4S8x5Cra2JDcVBcU-9ddrFin9PcyFAX-y2EUklNZKHn5RCGaP-H-A5_hgw23YU1TNi3MCFelWfoiYepuOf3eoy-fnj_ZXVOLj-dXaxOL8mW96ISB9KO0lOwynpuFCgQndHABRu9sZJzC3S0Gpizno6CcjCdEj01Wind6e4Yvf3F3e7G2dl1K5ZhGrY5zC3qkCAMf29i2AxX6WYQhgkt-wZ4fQ_I6fvOlTrMoazdNEF0aVcGppTQzahks776x3qddjm2egPrZdfepekCfPlnot9RHj7a_QT2X6fG</recordid><startdate>201501</startdate><enddate>201501</enddate><creator>Parsa, A F</creator><creator>Jahanshahi, B</creator><general>Clinics Cardive Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201501</creationdate><title>Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings</title><author>Parsa, A F ; Jahanshahi, B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p294t-ea5db5f0ad6df286a6a4387a241bf8d522da0bd7a1edf0b402a83649087667373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Body Mass Index</topic><topic>Cardiovascular Topics</topic><topic>Comorbidity</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - epidemiology</topic><topic>Coronary Artery Disease - prevention & control</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Iran - epidemiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Obesity - diagnosis</topic><topic>Obesity - epidemiology</topic><topic>Predictive Value of Tests</topic><topic>Prevalence</topic><topic>Prospective Studies</topic><topic>Protective Factors</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Waist-Hip Ratio</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parsa, A F</creatorcontrib><creatorcontrib>Jahanshahi, B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cardiovascular Journal of Africa</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Parsa, A F</au><au>Jahanshahi, B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings</atitle><jtitle>Cardiovascular Journal of Africa</jtitle><addtitle>Cardiovasc J Afr</addtitle><date>2015-01</date><risdate>2015</risdate><volume>26</volume><issue>1</issue><spage>13</spage><epage>16</epage><pages>13-16</pages><issn>1995-1892</issn><eissn>1680-0745</eissn><abstract>Although for decades there has been controversy regarding the relationship between obesity and coronary artery disease (CAD), it has been assumed that high body mass index (BMI) is a risk factor for CAD. However, the findings of some recent studies were paradoxical.
The aim of this study was to find a relationship between high BMI and waist-to-hip ratio (WHR) with severity of CAD.
This study was a cross-sectional, prospective study where 414 patients with suspected coronary artery disease, in whom coronary angiography was performed, were enrolled. The mean ± SD of their ages was 61.2 ± 27.4 years (range 25-84), and 250 (60.4%) were male. Regarding cardiovascular risk factors, 113 (27.3%) patients had a history of diabetes mellitus (DM), 162 (39.1%) had hypercholesterolaemia, 238 (57.4%) had hypertension, 109 (26.3%) were current smokers and 24 (5.8%) had a family history of CAD. The mean ± SD of the patients' BMI was 26.04 ± 4.08 kg/m(2) (range 16-39) and means ± SD of their WHR ranged from 0.951 ± 0.07 to 0.987 ± 0.05. The mean ± SD of the severity of CAD according to the SYNTAX and Duke scores were 17.7 ± 9.6 (range 0-64) and 3.2 ± 1.7 (range 0-12), respectively.
In this study, findings showed a negative correlation between the severity of CAD and BMI, according to both SYNTAX and Duke scores (p ≤ 0.001 and p = 0.001, respectively). However, there was a positive correlation between WHR and severity of CAD, according to the Duke score (p = 0.03).
BMI had a negative correlation with the severity of CAD, but waist-to-hip ratio had a positive correlation with severity of CAD.</abstract><cop>South Africa</cop><pub>Clinics Cardive Publishing</pub><pmid>25784312</pmid><doi>10.5830/CVJA-2014-054</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1995-1892 |
| ispartof | Cardiovascular Journal of Africa, 2015-01, Vol.26 (1), p.13-16 |
| issn | 1995-1892 1680-0745 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Aged Aged, 80 and over Body Mass Index Cardiovascular Topics Comorbidity Coronary Angiography Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - epidemiology Coronary Artery Disease - prevention & control Cross-Sectional Studies Female Humans Iran - epidemiology Male Middle Aged Obesity - diagnosis Obesity - epidemiology Predictive Value of Tests Prevalence Prospective Studies Protective Factors Risk Factors Severity of Illness Index Waist-Hip Ratio Young Adult |
| title | Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings |
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