Sphingosine 1-Phosphate Receptor 3-Deficient Dendritic Cells Modulate Splenic Responses to Ischemia-Reperfusion Injury

The plasticity of dendritic cells (DCs) permits phenotypic modulation ex vivo by gene expression or pharmacologic agents, and these modified DCs can exert therapeutic immunosuppressive effects in vivo through direct interactions with T cells, either inducing T regulatory cells (T(REG)s) or causing a...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2016-04, Vol.27 (4), p.1076-1090
Hauptverfasser:	Bajwa, Amandeep, Huang, Liping, Kurmaeva, Elvira, Gigliotti, Joseph C, Ye, Hong, Miller, Jacqueline, Rosin, Diane L, Lobo, Peter I, Okusa, Mark D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Research Bone Marrow Transplantation Dendritic Cells - transplantation Kidney - blood supply Male Mice Mice, Inbred C57BL Receptors, Lysosphingolipid - deficiency Reperfusion Injury - physiopathology Reperfusion Injury - surgery Spleen - physiopathology
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