Contractile function assessment by intraventricular balloon alters the ability of regional ischaemia to evoke ventricular fibrillation

Background and purpose In drug research using the rat Langendorff heart preparation, it is possible to study left ventricular (LV) contractility using an intraventricular balloon (IVB), and arrhythmogenesis during coronary ligation‐induced regional ischaemia. Assessing both concurrently would halve...

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Veröffentlicht in:	British journal of pharmacology 2016-01, Vol.173 (1), p.39-52
Hauptverfasser:	Wilder, Catherine D E, Masoud, Radwa, Yazar, Duygu, O'Brien, Brett A, Eykyn, Thomas R, Curtis, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiac arrhythmia Cardiac Catheters Electrocardiography Lactic Acid - metabolism Magnetic Resonance Spectroscopy Male Myocardial Contraction Myocardial Ischemia - pathology Myocardial Ischemia - physiopathology NMR Nuclear magnetic resonance Phosphorus - metabolism Rats Research Paper Research Papers Ventricular Fibrillation - drug therapy Ventricular Fibrillation - physiopathology Ventricular Function, Left Verapamil - therapeutic use
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