3,3′-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B–Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells

3,3′-Diindolylmethane (DIM), a natural indole found in cruciferous vegetables, has significant anti-cancer and anti-inflammatory properties. In this current study, we investigated the effects of DIM on acute lung injury (ALI) induced by exposure to staphylococcal enterotoxin B (SEB). We found that p...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2016-04, Vol.357 (1), p.177-187
Hauptverfasser: Elliott, David M., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
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Sprache:eng
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