Hyperfiltration and uricosuria in adolescents with type 1 diabetes

Background Urine uric acid (UUA) has been implicated in the pathogenesis of diabetic nephropathy via its effect on tubular cells. We hypothesized that the UUA level would be higher in adolescents with type 1 diabetes (T1D) than in those without T1D. We also hypothesized that UUA and fractional uric...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2016-05, Vol.31 (5), p.787-793
Hauptverfasser:	Bjornstad, Petter, Roncal, Carlos, Milagres, Tamara, Pyle, Laura, Lanaspa, Miguel Angel, Bishop, Franziska K., Snell-Bergeon, Janet K., Johnson, Richard J., Wadwa, R. Paul, Maahs, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors Biomarkers - blood Biomarkers - urine Blood pressure Care and treatment Case-Control Studies Child Creatinine - blood Cross-Sectional Studies Cystatin C - blood Development and progression Diabetes Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - diagnosis Diabetic nephropathies Diabetic Nephropathies - diagnosis Diabetic Nephropathies - etiology Diabetic Nephropathies - physiopathology Diabetic Nephropathies - urine Diabetic nephropathy Female Glomerular Filtration Rate Humans Hydrogen-Ion Concentration Kidney - physiopathology Male Measurement Medicine Medicine & Public Health Models, Biological Nephrology Original Article Pediatrics Physiological aspects Predictive Value of Tests Teenagers Up-Regulation Uric acid Uric Acid - urine Urine Urology Young Adult
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