Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci

Genetic risk loci have been identified for a wide range of diseases through genome-wide association studies (GWAS), but the relevant functional mechanisms have been identified for only a small proportion of these GWAS-identified loci. By integrating results from the largest current GWAS of chronic o...

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Veröffentlicht in:	Human molecular genetics 2015-02, Vol.24 (4), p.1200-1210
Hauptverfasser:	Castaldi, Peter J, Cho, Michael H, Zhou, Xiaobo, Qiu, Weiliang, Mcgeachie, Michael, Celli, Bartolome, Bakke, Per, Gulsvik, Amund, Lomas, David A, Crapo, James D, Beaty, Terri H, Rennard, Stephen, Harshfield, Benjamin, Lange, Christoph, Singh, Dave, Tal-Singer, Ruth, Riley, John H, Quackenbush, John, Raby, Benjamin A, Carey, Vincent J, Silverman, Edwin K, Hersh, Craig P
Format:	Artikel
Sprache:	eng
Schlagworte:	Association Studies Case-Control Studies Chromosome Mapping Chromosomes, Human, Pair 15 Computational Biology Enhancer Elements, Genetic Gene Expression Gene Expression Regulation Genetic Linkage Genetic Predisposition to Disease Genome-Wide Association Study Humans Linkage Disequilibrium Polymorphism, Single Nucleotide Pulmonary Disease, Chronic Obstructive - genetics Quantitative Trait Loci Smoking
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