Identification of chondrocyte-binding peptides by phage display

ABSTRACT As an initial step toward targeting cartilage tissue for potential therapeutic applications, we sought cartilage‐binding peptides using phage display, a powerful technology for selection of peptides that bind to molecules of interest. A library of phage displaying random 12‐amino acid pepti...

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Veröffentlicht in:	Journal of orthopaedic research 2013-07, Vol.31 (7), p.1053-1058
Hauptverfasser:	Cheung, Crystal S.F., Lui, Julian C., Baron, Jeffrey
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Animals Bacteriophages - metabolism cartilage Cartilage - metabolism Cell Surface Display Techniques - methods Cells, Cultured chondrocytes Chondrocytes - cytology Chondrocytes - metabolism Extracellular Matrix - metabolism Male Mice Mice, Inbred C57BL peptide Peptides - metabolism phage display Protein Binding targeted therapy
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