Integrated molecular mechanism directing nucleosome reorganization by human FACT

Facilitates chromatin transcription (FACT) plays essential roles in chromatin remodeling during DNA transcription, replication, and repair. Our structural and biochemical studies of human FACT-histone interactions present precise views of nucleosome reorganization, conducted by the FACT-SPT16 (suppr...

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Veröffentlicht in:	Genes & development 2016-03, Vol.30 (6), p.673-686
Hauptverfasser:	Tsunaka, Yasuo, Fujiwara, Yoshie, Oyama, Takuji, Hirose, Susumu, Morikawa, Kosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystallization Cytidine Deaminase - metabolism DNA - metabolism DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism High Mobility Group Proteins - chemistry High Mobility Group Proteins - genetics High Mobility Group Proteins - metabolism Histones - chemistry Histones - metabolism Humans Models, Molecular Mutation Nucleosomes - metabolism Protein Binding Protein Structure, Quaternary Research Paper Transcriptional Elongation Factors - chemistry Transcriptional Elongation Factors - genetics Transcriptional Elongation Factors - metabolism
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