Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

Exercise provides many health benefits, including improved metabolism, cardiovascular health, and cognition. We have shown previously that FNDC5, a type I transmembrane protein, and its circulating form, irisin, convey some of these benefits in mice. However, recent reports questioned the existence...

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Veröffentlicht in:	Cell metabolism 2015-10, Vol.22 (4), p.734-740
Hauptverfasser:	Jedrychowski, Mark P., Wrann, Christiane D., Paulo, Joao A., Gerber, Kaitlyn K., Szpyt, John, Robinson, Matthew M., Nair, K. Sreekumaran, Gygi, Steven P., Spiegelman, Bruce M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acid Sequence Body Mass Index Chromatography, High Pressure Liquid Electrophoresis, Polyacrylamide Gel Exercise Fibronectins - blood Fibronectins - metabolism Humans Isotope Labeling Male Molecular Sequence Data Peptides - analysis Tandem Mass Spectrometry Young Adult
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