Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes
ObjectiveAmong indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also s...
Gespeichert in:
| Veröffentlicht in: | BMJ open diabetes research & care 2016, Vol.4 (1), p.e000188-e000188 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e000188 |
|---|---|
| container_issue | 1 |
| container_start_page | e000188 |
| container_title | BMJ open diabetes research & care |
| container_volume | 4 |
| creator | Bouchi, Ryotaro Asakawa, Masahiro Ohara, Norihiko Nakano, Yujiro Takeuchi, Takato Murakami, Masanori Sasahara, Yuriko Numasawa, Mitsuyuki Minami, Isao Izumiyama, Hajime Hashimoto, Koshi Yoshimoto, Takanobu Ogawa, Yoshihiro |
| description | ObjectiveAmong indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes.MethodsThis is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness.ResultsABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p |
| doi_str_mv | 10.1136/bmjdrc-2015-000188 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4800068</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4033726861</sourcerecordid><originalsourceid>FETCH-LOGICAL-b468t-2bdbb8591a0f170227cb37aca1c7420640d94f8d58e9dfe2002950d3ceef23903</originalsourceid><addsrcrecordid>eNqNkc1u1DAUhSMEolXpC7BAltiURcA_SexskKYVpSNVYlFYW459zXg0iYPttMyuL8C-vF6fpB6lVG1XrHwlf-fonnuK4i3BHwlhzaeuX5ugS4pJXWKMiRAvin2Ka1pWouUvH817xWGM6x3DGsJE_brYoxzTRuB2v_izHIwLoBPqQcUpAPIWXbqoIagNUsaNPrq0RbfXNwt07M0WXazUCCjL4Pft9V90tDi-WH5ALiIVo9dOJTDoyqUVUiFBcNklJmftADEiN6BRJQdDijOTttmLIuNUBwnim-KVVZsIh_fvQfHj9Mv3k7Py_NvX5cnivOyqRqSSdqbrRN0ShS3JUSjXHeNKK6J5RXFTYdNWVphaQGssUIxpW2PDNIClrMXsoPg8-45T14PReaEcV47B9SpspVdOPv0Z3Er-9JeyEvmOjcgGR_cGwf-aICbZ72622agB_BQl4ZxXQuC6yuj7Z-jaT2HI8TIlWMsoYzxTdKZ08DEGsA_LECx3hcu5cLkrXM6FZ9G7xzEeJP_qzUA5A1n8P4Z3txK5MQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1783932337</pqid></control><display><type>article</type><title>Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes</title><source>BMJ Open Access Journals</source><source>PubMed Central</source><source>Directory of Open Access Journals</source><source>EZB Electronic Journals Library</source><source>PubMed Central Open Access</source><creator>Bouchi, Ryotaro ; Asakawa, Masahiro ; Ohara, Norihiko ; Nakano, Yujiro ; Takeuchi, Takato ; Murakami, Masanori ; Sasahara, Yuriko ; Numasawa, Mitsuyuki ; Minami, Isao ; Izumiyama, Hajime ; Hashimoto, Koshi ; Yoshimoto, Takanobu ; Ogawa, Yoshihiro</creator><creatorcontrib>Bouchi, Ryotaro ; Asakawa, Masahiro ; Ohara, Norihiko ; Nakano, Yujiro ; Takeuchi, Takato ; Murakami, Masanori ; Sasahara, Yuriko ; Numasawa, Mitsuyuki ; Minami, Isao ; Izumiyama, Hajime ; Hashimoto, Koshi ; Yoshimoto, Takanobu ; Ogawa, Yoshihiro</creatorcontrib><description>ObjectiveAmong indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes.MethodsThis is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness.ResultsABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate.ConclusionsABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.</description><identifier>ISSN: 2052-4897</identifier><identifier>EISSN: 2052-4897</identifier><identifier>DOI: 10.1136/bmjdrc-2015-000188</identifier><identifier>PMID: 27026809</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Blood pressure ; Body mass index ; Cardiovascular and Metabolic Risk ; Heart attacks ; Insulin resistance ; Mortality</subject><ispartof>BMJ open diabetes research & care, 2016, Vol.4 (1), p.e000188-e000188</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing</rights><rights>Copyright: 2016 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing</rights><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b468t-2bdbb8591a0f170227cb37aca1c7420640d94f8d58e9dfe2002950d3ceef23903</citedby><cites>FETCH-LOGICAL-b468t-2bdbb8591a0f170227cb37aca1c7420640d94f8d58e9dfe2002950d3ceef23903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://drc.bmj.com/content/4/1/e000188.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttp://drc.bmj.com/content/4/1/e000188.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,4010,27526,27527,27900,27901,27902,53766,53768,77343,77374</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27026809$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bouchi, Ryotaro</creatorcontrib><creatorcontrib>Asakawa, Masahiro</creatorcontrib><creatorcontrib>Ohara, Norihiko</creatorcontrib><creatorcontrib>Nakano, Yujiro</creatorcontrib><creatorcontrib>Takeuchi, Takato</creatorcontrib><creatorcontrib>Murakami, Masanori</creatorcontrib><creatorcontrib>Sasahara, Yuriko</creatorcontrib><creatorcontrib>Numasawa, Mitsuyuki</creatorcontrib><creatorcontrib>Minami, Isao</creatorcontrib><creatorcontrib>Izumiyama, Hajime</creatorcontrib><creatorcontrib>Hashimoto, Koshi</creatorcontrib><creatorcontrib>Yoshimoto, Takanobu</creatorcontrib><creatorcontrib>Ogawa, Yoshihiro</creatorcontrib><title>Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes</title><title>BMJ open diabetes research & care</title><addtitle>BMJ Open Diabetes Res Care</addtitle><description>ObjectiveAmong indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes.MethodsThis is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness.ResultsABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate.ConclusionsABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.</description><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Cardiovascular and Metabolic Risk</subject><subject>Heart attacks</subject><subject>Insulin resistance</subject><subject>Mortality</subject><issn>2052-4897</issn><issn>2052-4897</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkc1u1DAUhSMEolXpC7BAltiURcA_SexskKYVpSNVYlFYW459zXg0iYPttMyuL8C-vF6fpB6lVG1XrHwlf-fonnuK4i3BHwlhzaeuX5ugS4pJXWKMiRAvin2Ka1pWouUvH817xWGM6x3DGsJE_brYoxzTRuB2v_izHIwLoBPqQcUpAPIWXbqoIagNUsaNPrq0RbfXNwt07M0WXazUCCjL4Pft9V90tDi-WH5ALiIVo9dOJTDoyqUVUiFBcNklJmftADEiN6BRJQdDijOTttmLIuNUBwnim-KVVZsIh_fvQfHj9Mv3k7Py_NvX5cnivOyqRqSSdqbrRN0ShS3JUSjXHeNKK6J5RXFTYdNWVphaQGssUIxpW2PDNIClrMXsoPg8-45T14PReaEcV47B9SpspVdOPv0Z3Er-9JeyEvmOjcgGR_cGwf-aICbZ72622agB_BQl4ZxXQuC6yuj7Z-jaT2HI8TIlWMsoYzxTdKZ08DEGsA_LECx3hcu5cLkrXM6FZ9G7xzEeJP_qzUA5A1n8P4Z3txK5MQ</recordid><startdate>2016</startdate><enddate>2016</enddate><creator>Bouchi, Ryotaro</creator><creator>Asakawa, Masahiro</creator><creator>Ohara, Norihiko</creator><creator>Nakano, Yujiro</creator><creator>Takeuchi, Takato</creator><creator>Murakami, Masanori</creator><creator>Sasahara, Yuriko</creator><creator>Numasawa, Mitsuyuki</creator><creator>Minami, Isao</creator><creator>Izumiyama, Hajime</creator><creator>Hashimoto, Koshi</creator><creator>Yoshimoto, Takanobu</creator><creator>Ogawa, Yoshihiro</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>2016</creationdate><title>Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes</title><author>Bouchi, Ryotaro ; Asakawa, Masahiro ; Ohara, Norihiko ; Nakano, Yujiro ; Takeuchi, Takato ; Murakami, Masanori ; Sasahara, Yuriko ; Numasawa, Mitsuyuki ; Minami, Isao ; Izumiyama, Hajime ; Hashimoto, Koshi ; Yoshimoto, Takanobu ; Ogawa, Yoshihiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b468t-2bdbb8591a0f170227cb37aca1c7420640d94f8d58e9dfe2002950d3ceef23903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Blood pressure</topic><topic>Body mass index</topic><topic>Cardiovascular and Metabolic Risk</topic><topic>Heart attacks</topic><topic>Insulin resistance</topic><topic>Mortality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bouchi, Ryotaro</creatorcontrib><creatorcontrib>Asakawa, Masahiro</creatorcontrib><creatorcontrib>Ohara, Norihiko</creatorcontrib><creatorcontrib>Nakano, Yujiro</creatorcontrib><creatorcontrib>Takeuchi, Takato</creatorcontrib><creatorcontrib>Murakami, Masanori</creatorcontrib><creatorcontrib>Sasahara, Yuriko</creatorcontrib><creatorcontrib>Numasawa, Mitsuyuki</creatorcontrib><creatorcontrib>Minami, Isao</creatorcontrib><creatorcontrib>Izumiyama, Hajime</creatorcontrib><creatorcontrib>Hashimoto, Koshi</creatorcontrib><creatorcontrib>Yoshimoto, Takanobu</creatorcontrib><creatorcontrib>Ogawa, Yoshihiro</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ open diabetes research & care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bouchi, Ryotaro</au><au>Asakawa, Masahiro</au><au>Ohara, Norihiko</au><au>Nakano, Yujiro</au><au>Takeuchi, Takato</au><au>Murakami, Masanori</au><au>Sasahara, Yuriko</au><au>Numasawa, Mitsuyuki</au><au>Minami, Isao</au><au>Izumiyama, Hajime</au><au>Hashimoto, Koshi</au><au>Yoshimoto, Takanobu</au><au>Ogawa, Yoshihiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes</atitle><jtitle>BMJ open diabetes research & care</jtitle><addtitle>BMJ Open Diabetes Res Care</addtitle><date>2016</date><risdate>2016</risdate><volume>4</volume><issue>1</issue><spage>e000188</spage><epage>e000188</epage><pages>e000188-e000188</pages><issn>2052-4897</issn><eissn>2052-4897</eissn><abstract>ObjectiveAmong indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes.MethodsThis is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness.ResultsABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate.ConclusionsABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>27026809</pmid><doi>10.1136/bmjdrc-2015-000188</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2052-4897 |
| ispartof | BMJ open diabetes research & care, 2016, Vol.4 (1), p.e000188-e000188 |
| issn | 2052-4897 2052-4897 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4800068 |
| source | BMJ Open Access Journals; PubMed Central; Directory of Open Access Journals; EZB Electronic Journals Library; PubMed Central Open Access |
| subjects | Blood pressure Body mass index Cardiovascular and Metabolic Risk Heart attacks Insulin resistance Mortality |
| title | Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T18%3A04%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Indirect%20measure%20of%20visceral%20adiposity%20%E2%80%98A%20Body%20Shape%20Index%E2%80%99%20(ABSI)%20is%20associated%20with%20arterial%20stiffness%20in%20patients%20with%20type%202%20diabetes&rft.jtitle=BMJ%20open%20diabetes%20research%20&%20care&rft.au=Bouchi,%20Ryotaro&rft.date=2016&rft.volume=4&rft.issue=1&rft.spage=e000188&rft.epage=e000188&rft.pages=e000188-e000188&rft.issn=2052-4897&rft.eissn=2052-4897&rft_id=info:doi/10.1136/bmjdrc-2015-000188&rft_dat=%3Cproquest_pubme%3E4033726861%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1783932337&rft_id=info:pmid/27026809&rfr_iscdi=true |