Angiotensin II increases gene expression after selective intra-arterial adenovirus delivery in a rabbit model assessed using in vivo SSTR2-based reporter imaging

Background Gene therapy has been hampered by low expression upon in vivo delivery. Using a somatostatin receptor type 2 (SSTR2)-based reporter, we assessed whether angiotensin II (AII) can improve gene expression by adenovirus upon intra-arterial (IA) delivery in a large animal model. Methods A SSTR...

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Veröffentlicht in:	EJNMMI research 2016-03, Vol.6 (1), p.25-25, Article 25
Hauptverfasser:	Singh, Sheela P., Ravoori, Murali K., Dixon, Katherine A., Han, Lin, Gupta, Sanjay, Uthamanthil, Rajesh, Wright, Kenneth C., Kundra, Vikas
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac Imaging Imaging Medicine Medicine & Public Health Nuclear Medicine Oncology Original Research Orthopedics Radiology
Online-Zugang:	Volltext
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