CD36 regulates lipopolysaccharide-induced signaling pathways and mediates the internalization of Escherichia coli in cooperation with TLR4 in goat mammary gland epithelial cells

The scavenger receptor CD36 is involved in pathogen recognition, phagocytosis, and pathogen-induced signaling. This study investigated the relationship between CD36 and TLR4 in modifying lipopolysaccharide (LPS)-induced signaling pathways and mediating Escherichia coli ( E. coli ) endocytosis in pri...

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Veröffentlicht in:	Scientific reports 2016-03, Vol.6 (1), p.23132-23132, Article 23132
Hauptverfasser:	Cao, Duoyao, Luo, Jun, Chen, Dekun, Xu, Huifen, Shi, Huaiping, Jing, Xiaoqi, Zang, Wenjuan
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/89 14/19 38/109 38/77 42/35 631/250/255/1318 631/250/256/2516 82/80 96/1 96/21 Activator protein 1 Adaptor proteins Animals c-Jun protein CD36 antigen CD36 Antigens - metabolism Cooperation Cooperativity Cytokines - metabolism E coli Endocytosis Epithelial cells Epithelial Cells - metabolism Epithelial Cells - microbiology Escherichia coli Escherichia coli - physiology Female Gene expression Goats Humanities and Social Sciences Inflammation Internalization JNK Mitogen-Activated Protein Kinases - metabolism JNK protein Kinases Lipopolysaccharides Lipopolysaccharides - pharmacology Mammary gland Mammary Glands, Animal - metabolism Mammary Glands, Animal - microbiology Mastitis multidisciplinary NF-kappa B - metabolism Pathogens Phagocytosis Scavenger receptors Science Signal Transduction TLR4 protein Toll-Like Receptor 4 - metabolism Toll-like receptors Transcription Factor AP-1 - metabolism Transcription factors
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