Two methods of whole-genome amplification enable accurate genotyping across a 2320-SNP linkage panel

Comprehensive genome scans involving many thousands of SNP assays will require significant amounts of genomic DNA from each sample. We report two successful methods for amplifying whole-genomic DNA prior to SNP analysis, multiple displacement amplification, and OmniPlex technology. We determined the...

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Veröffentlicht in:	Genome research 2004-05, Vol.14 (5), p.901-907
Hauptverfasser:	Barker, David L, Hansen, Mark S T, Faruqi, A Fawad, Giannola, Diane, Irsula, Orlando R, Lasken, Roger S, Latterich, Martin, Makarov, Vladimir, Oliphant, Arnold, Pinter, Jonathon H, Shen, Richard, Sleptsova, Irina, Ziehler, William, Lai, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - genetics Genetic Linkage - genetics Genome, Human Genotype Humans Methods Nucleic Acid Amplification Techniques - methods Nucleic Acid Amplification Techniques - standards Polymorphism, Single Nucleotide - genetics Reproducibility of Results
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