Physical activity in advanced cancer patients: a systematic review protocol

Progressive, incurable cancer is associated with increased fatigue, increased muscle weakness, and reduced physical functioning, all of which negatively impact quality of life. Physical activity has demonstrated benefits on cancer-related fatigue and physical functioning in early-stage cancer patien...

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Veröffentlicht in:Systematic Reviews 2016-03, Vol.5 (1), p.43-43, Article 43
Hauptverfasser: Lowe, Sonya S, Tan, Maria, Faily, Joan, Watanabe, Sharon M, Courneya, Kerry S
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container_title Systematic Reviews
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creator Lowe, Sonya S
Tan, Maria
Faily, Joan
Watanabe, Sharon M
Courneya, Kerry S
description Progressive, incurable cancer is associated with increased fatigue, increased muscle weakness, and reduced physical functioning, all of which negatively impact quality of life. Physical activity has demonstrated benefits on cancer-related fatigue and physical functioning in early-stage cancer patients; however, its impact on these outcomes in end-stage cancer has not been established. The aim of this systematic review is to determine the potential benefits, harms, and effects of physical activity interventions on quality of life outcomes in advanced cancer patients. A systematic review of peer-reviewed literature on physical activity in advanced cancer patients will be undertaken. Empirical quantitative studies will be considered for inclusion if they present interventional or observational data on physical activity in advanced cancer patients. Searches will be conducted in the following electronic databases: CINAHL; CIRRIE Database of International Rehabilitation Research; Cochrane Database of Systematic Reviews (CDSR); Database of Abstracts of Reviews of Effects (DARE); Cochrane Central Register of Controlled Trials (CENTRAL); EMBASE; MEDLINE; PEDro: the Physiotherapy Evidence Database; PQDT; PsycInfo; PubMed; REHABDATA; Scopus; SPORTDiscus; and Web of Science, to identify relevant studies of interest. Additional strategies to identify relevant studies will include citation searches and evaluation of reference lists of included articles. Titles, abstracts, and keywords of identified studies from the search strategies will be screened for inclusion criteria. Two independent reviewers will conduct quality appraisal using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies (EPHPP) and the Cochrane risk of bias tool. A descriptive summary of included studies will describe the study designs, participant and activity characteristics, and objective and patient-reported outcomes. This systematic review will summarize the current evidence base on physical activity interventions in advanced cancer patients. The findings from this systematic review will identify gaps to be explored by future research studies and inform future practice guideline development of physical activity interventions in advanced cancer patients. PROSPERO CRD42015026281.
doi_str_mv 10.1186/s13643-016-0220-x
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A descriptive summary of included studies will describe the study designs, participant and activity characteristics, and objective and patient-reported outcomes. This systematic review will summarize the current evidence base on physical activity interventions in advanced cancer patients. The findings from this systematic review will identify gaps to be explored by future research studies and inform future practice guideline development of physical activity interventions in advanced cancer patients. PROSPERO CRD42015026281.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>26968701</pmid><doi>10.1186/s13643-016-0220-x</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
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subjects Bias
Cancer
Cancer patients
Care and treatment
Evidence-based medicine
Exercise
Exercise Therapy - methods
Fatigue - etiology
Fatigue - rehabilitation
Humans
Intervention
Metastasis
Motor Activity
Neoplasms - complications
Neoplasms - pathology
Neoplasms - rehabilitation
Palliative care
Palliative Care - methods
Palliative treatment
Patients
Physical fitness
Protocol
Public health
Quality of Life
Systematic review
Terminal Care - methods
title Physical activity in advanced cancer patients: a systematic review protocol
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