Paclitaxel injection concentrate for nanodispersion versus nab-paclitaxel in women with metastatic breast cancer: a multicenter, randomized, comparative phase II/III study

Paclitaxel is widely used in the treatment of patients with metastatic breast cancer (MBC). Formulations of paclitaxel contain surfactants and solvents or albumin derived from human blood. The use of co-solvents such as polyoxyethylated castor oil is thought to contribute to toxicity profile and hyp...

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Veröffentlicht in:	Breast cancer research and treatment 2016-02, Vol.156 (1), p.125-134
Hauptverfasser:	Jain, Minish M., Gupte, Smita U., Patil, Shekhar G., Pathak, Anand B., Deshmukh, Chetan D., Bhatt, Niraj, Haritha, Chiramana, Govind Babu, K., Bondarde, Shailesh A., Digumarti, Raghunadharao, Bajpai, Jyoti, Kumar, Ravi, Bakshi, Ashish V., Bhattacharya, Gouri Sankar, Patil, Poonam, Subramanian, Sundaram, Vaid, Ashok K., Desai, Chirag J., Khopade, Ajay, Chimote, Geetanjali, Bapsy, Poonamalle P., Bhowmik, Shravanti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Albumins - administration & dosage Albumins - therapeutic use Antineoplastic Agents - administration & dosage Antineoplastic Agents - therapeutic use Biochemistry Breast cancer Breast Neoplasms - drug therapy Cancer metastasis Cancer research Cancer therapies Care and treatment Castor oil Clinical Trial Comparative analysis Female Humans Injections Medicine Medicine & Public Health Middle Aged Neoplasm Metastasis Oncology Paclitaxel Paclitaxel - administration & dosage Paclitaxel - therapeutic use Pharmaceuticals Phthalates Polyvinyl chloride Studies Survival Analysis Treatment Outcome Young Adult
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