PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

OBJECTIVE:The aim of this study is to identify single-nucleotide polymorphisms (SNPs) influencing blood pressure (BP) response to the β-blocker atenolol. METHODS:Genome-wide association analysis of BP response to atenolol monotherapy was performed in 233 white participants with uncomplicated hyperte...

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Veröffentlicht in:	Journal of hypertension 2015-11, Vol.33 (11), p.2278-2285
Hauptverfasser:	Gong, Yan, McDonough, Caitrin W, Beitelshees, Amber L, Rouby, Nihal El, Hiltunen, Timo P, O’Connell, Jeffrey R, Padmanabhan, Sandosh, Langaee, Taimour Y, Hall, Karen, Schmidt, Siegfried O.F, Curry, Robert W, Gums, John G, Donner, Kati M, Kontula, Kimmo K, Bailey, Kent R, Boerwinkle, Eric, Takahashi, Atsushi, Tanaka, Toshihiro, Kubo, Michiaki, Chapman, Arlene B, Turner, Stephen T, Pepine, Carl J, Cooper-DeHoff, Rhonda M, Johnson, Julie A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - therapeutic use Adult African Continental Ancestry Group - genetics Aged Antihypertensive Agents - therapeutic use Atenolol - therapeutic use Blood Pressure - drug effects Blood Pressure - genetics Essential Hypertension European Continental Ancestry Group - genetics Female Genome-Wide Association Study Humans Hypertension - drug therapy Hypertension - genetics Male Middle Aged Pharmacogenetics Polymorphism, Single Nucleotide Receptor-Like Protein Tyrosine Phosphatases, Class 2 - genetics
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