Neutrophil elastase‐deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis

Essentials Neutrophil elastase (NE) plays a role in extracellular trap formation (NETosis) triggered by microbes. The contribution of NE was evaluated in mouse NETosis models of sterile inflammation and thrombosis. NE is not required for mouse neutrophil NET production in vitro with non‐infectious s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of thrombosis and haemostasis 2016-03, Vol.14 (3), p.551-558
Hauptverfasser:	Martinod, K., Witsch, T., Farley, K., Gallant, M., Remold‐O'Donnell, E., Wagner, D. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Disease Models, Animal eukocyte elastase extracellular traps Extracellular Traps - metabolism Genotype Ionomycin - pharmacology Leukocyte Elastase - deficiency Leukocyte Elastase - genetics Mice, Inbred C57BL Mice, Knockout Neutrophil Activation Neutrophils Neutrophils - drug effects Neutrophils - enzymology Phenotype Rodents serine proteases Tetradecanoylphorbol Acetate - pharmacology Thrombosis venous thrombosis Venous Thrombosis - blood Venous Thrombosis - enzymology Venous Thrombosis - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!