IL-10+ innate-like B cells are part of the skin immune system and require α4β1 integrin to migrate between the peritoneum and inflamed skin1

The skin is an important barrier organ and frequent target of autoimmunity and allergy. Here we found innate-like B cells that expressed the anti-inflammatory cytokine IL-10 in the skin of humans and mice. Unexpectedly, innate-like B1 and conventional B2 cells showed differential homing capacities w...

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Veröffentlicht in:	The Journal of immunology (1950) 2016-02, Vol.196 (6), p.2514-2525
Hauptverfasser:	Geherin, Skye A., Gómez, Daniela, Glabman, Raisa A., Ruthel, Gordon, Hamann, Alf, Debes, Gudrun F.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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