Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction
The aim of this study was to evaluate biochemical parameters in serum of women with preeclampsia and IUGR. A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women wi...
Gespeichert in:
| Veröffentlicht in: | Medicinski arhiv 2016-02, Vol.70 (1), p.44-47 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 47 |
|---|---|
| container_issue | 1 |
| container_start_page | 44 |
| container_title | Medicinski arhiv |
| container_volume | 70 |
| creator | Dacaj, Ramadan Izetbegovic, Sebija Stojkanovic, Goran Dreshaj, Skender |
| description | The aim of this study was to evaluate biochemical parameters in serum of women with preeclampsia and IUGR.
A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=60). Outcome measures were following values of biochemical parameters in serum of mother and fetuses: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), bilirubin (indirect and direct) and cholesterol. A blood for analysis was drawn from the cubital vein of mothers and the umbilical vein of the fetuses during delivery period.
The mean of maternal age was 30.0±6.1 years in women with preeclampsia and IUGR and 28.1±5.1 years in healthy pregnant women, p > 0.05. The most of women with preeclampsia and IUGR had grade III of placental maturation (48.3%). There is a significant association between the placental maturation and the diagnosis, p < 0.001. There was a statistically significant difference in body mass of newborns between IUGR and non IUGR groups, p < 0.001. There was a significant statistically difference in serum value of AST, ALT, LDH and total cholesterol between women with preeclampsia and IUGR and healthy pregnant women (all p < 0.001).
Measurement of AST, ALT, LDH, and total cholesterol in serum of pregnant women and newborns with IUGR allows the differentiation and threatening risk of perinatal complications due to hypoxia. |
| doi_str_mv | 10.5455/medarh.2016.70.44-47 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4779350</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3959662951</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3517-2e14496824348c4077d72f1c814d2ce60e5495ed79ea5dfecfc07b6e4b90c2bf3</originalsourceid><addsrcrecordid>eNpdUU1rGzEQFaEhcdP-g1AEvfSyjqTVx-pSKMZNA4aUJoXehKydjRV2JUfadUl_fWWchqSnGZg3j_eB0Dklc8GFuBigtWkzZ4TKuSJzziuujtCM6kZWQkv6Bs1ILUhFtf51it7mfE-I0IrpE3TKpG6IrukM3Sx72NkRWrzyO0h4Gf48DpCxD3hhc1lih78nANfbYZu9xTa0-CqMyU4jJB8AX6b4e9zgH5DH5N3oY3iHjjvbZ3j_NM_Qz6_L28W3anV9ebX4sqpcLaiqGFDOtWwYr3njOFGqVayjrqG8ZQ4kAcG1gFZpsKLtwHWOqLUEvtbEsXVXn6HPB97ttC5pONjL6s02-cGmRxOtN68vwW_MXdwZrpQu0RSCT08EKT5MxYAZfHbQ9zZAnLKhSnEqa0ZUgX78D3ofpxSKvYKSikhJ2Z6QH1AuxZwTdM9iKDH71syhNbNvzShiOC9iytuHl0aen_7VVP8F_nGV9g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1767066120</pqid></control><display><type>article</type><title>Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction</title><source>MEDLINE</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Dacaj, Ramadan ; Izetbegovic, Sebija ; Stojkanovic, Goran ; Dreshaj, Skender</creator><creatorcontrib>Dacaj, Ramadan ; Izetbegovic, Sebija ; Stojkanovic, Goran ; Dreshaj, Skender</creatorcontrib><description>The aim of this study was to evaluate biochemical parameters in serum of women with preeclampsia and IUGR.
A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=60). Outcome measures were following values of biochemical parameters in serum of mother and fetuses: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), bilirubin (indirect and direct) and cholesterol. A blood for analysis was drawn from the cubital vein of mothers and the umbilical vein of the fetuses during delivery period.
The mean of maternal age was 30.0±6.1 years in women with preeclampsia and IUGR and 28.1±5.1 years in healthy pregnant women, p > 0.05. The most of women with preeclampsia and IUGR had grade III of placental maturation (48.3%). There is a significant association between the placental maturation and the diagnosis, p < 0.001. There was a statistically significant difference in body mass of newborns between IUGR and non IUGR groups, p < 0.001. There was a significant statistically difference in serum value of AST, ALT, LDH and total cholesterol between women with preeclampsia and IUGR and healthy pregnant women (all p < 0.001).
Measurement of AST, ALT, LDH, and total cholesterol in serum of pregnant women and newborns with IUGR allows the differentiation and threatening risk of perinatal complications due to hypoxia.</description><identifier>ISSN: 0350-199X</identifier><identifier>EISSN: 1986-5961</identifier><identifier>DOI: 10.5455/medarh.2016.70.44-47</identifier><identifier>PMID: 26980931</identifier><language>eng</language><publisher>Bosnia and Herzegovina: Academy of Medical Sciences of Bosnia and Herzegovina</publisher><subject>Adult ; Alanine Transaminase - blood ; Aspartate Aminotransferases - blood ; Bilirubin - blood ; Biomarkers - blood ; Birth Weight ; Body Mass Index ; Cholesterol - blood ; Female ; Fetal Growth Retardation - blood ; Fetal Growth Retardation - diagnosis ; Humans ; Infant, Newborn ; L-Lactate Dehydrogenase - blood ; Original Paper ; Pre-Eclampsia - blood ; Pre-Eclampsia - diagnosis ; Predictive Value of Tests ; Pregnancy ; Prognosis ; Prospective Studies ; Sensitivity and Specificity</subject><ispartof>Medicinski arhiv, 2016-02, Vol.70 (1), p.44-47</ispartof><rights>Copyright Academy of Medical Sciences of Bosnia and Herzegovina 2016</rights><rights>Copyright: © Ramadan Dacaj, Sebija Izetbegovic, Goran Stojkanovic, Skender Dresha 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3517-2e14496824348c4077d72f1c814d2ce60e5495ed79ea5dfecfc07b6e4b90c2bf3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779350/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779350/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27915,27916,53782,53784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26980931$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dacaj, Ramadan</creatorcontrib><creatorcontrib>Izetbegovic, Sebija</creatorcontrib><creatorcontrib>Stojkanovic, Goran</creatorcontrib><creatorcontrib>Dreshaj, Skender</creatorcontrib><title>Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction</title><title>Medicinski arhiv</title><addtitle>Med Arch</addtitle><description>The aim of this study was to evaluate biochemical parameters in serum of women with preeclampsia and IUGR.
A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=60). Outcome measures were following values of biochemical parameters in serum of mother and fetuses: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), bilirubin (indirect and direct) and cholesterol. A blood for analysis was drawn from the cubital vein of mothers and the umbilical vein of the fetuses during delivery period.
The mean of maternal age was 30.0±6.1 years in women with preeclampsia and IUGR and 28.1±5.1 years in healthy pregnant women, p > 0.05. The most of women with preeclampsia and IUGR had grade III of placental maturation (48.3%). There is a significant association between the placental maturation and the diagnosis, p < 0.001. There was a statistically significant difference in body mass of newborns between IUGR and non IUGR groups, p < 0.001. There was a significant statistically difference in serum value of AST, ALT, LDH and total cholesterol between women with preeclampsia and IUGR and healthy pregnant women (all p < 0.001).
Measurement of AST, ALT, LDH, and total cholesterol in serum of pregnant women and newborns with IUGR allows the differentiation and threatening risk of perinatal complications due to hypoxia.</description><subject>Adult</subject><subject>Alanine Transaminase - blood</subject><subject>Aspartate Aminotransferases - blood</subject><subject>Bilirubin - blood</subject><subject>Biomarkers - blood</subject><subject>Birth Weight</subject><subject>Body Mass Index</subject><subject>Cholesterol - blood</subject><subject>Female</subject><subject>Fetal Growth Retardation - blood</subject><subject>Fetal Growth Retardation - diagnosis</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>L-Lactate Dehydrogenase - blood</subject><subject>Original Paper</subject><subject>Pre-Eclampsia - blood</subject><subject>Pre-Eclampsia - diagnosis</subject><subject>Predictive Value of Tests</subject><subject>Pregnancy</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Sensitivity and Specificity</subject><issn>0350-199X</issn><issn>1986-5961</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdUU1rGzEQFaEhcdP-g1AEvfSyjqTVx-pSKMZNA4aUJoXehKydjRV2JUfadUl_fWWchqSnGZg3j_eB0Dklc8GFuBigtWkzZ4TKuSJzziuujtCM6kZWQkv6Bs1ILUhFtf51it7mfE-I0IrpE3TKpG6IrukM3Sx72NkRWrzyO0h4Gf48DpCxD3hhc1lih78nANfbYZu9xTa0-CqMyU4jJB8AX6b4e9zgH5DH5N3oY3iHjjvbZ3j_NM_Qz6_L28W3anV9ebX4sqpcLaiqGFDOtWwYr3njOFGqVayjrqG8ZQ4kAcG1gFZpsKLtwHWOqLUEvtbEsXVXn6HPB97ttC5pONjL6s02-cGmRxOtN68vwW_MXdwZrpQu0RSCT08EKT5MxYAZfHbQ9zZAnLKhSnEqa0ZUgX78D3ofpxSKvYKSikhJ2Z6QH1AuxZwTdM9iKDH71syhNbNvzShiOC9iytuHl0aen_7VVP8F_nGV9g</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Dacaj, Ramadan</creator><creator>Izetbegovic, Sebija</creator><creator>Stojkanovic, Goran</creator><creator>Dreshaj, Skender</creator><general>Academy of Medical Sciences of Bosnia and Herzegovina</general><general>AVICENA, d.o.o., Sarajevo</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160201</creationdate><title>Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction</title><author>Dacaj, Ramadan ; Izetbegovic, Sebija ; Stojkanovic, Goran ; Dreshaj, Skender</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3517-2e14496824348c4077d72f1c814d2ce60e5495ed79ea5dfecfc07b6e4b90c2bf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Alanine Transaminase - blood</topic><topic>Aspartate Aminotransferases - blood</topic><topic>Bilirubin - blood</topic><topic>Biomarkers - blood</topic><topic>Birth Weight</topic><topic>Body Mass Index</topic><topic>Cholesterol - blood</topic><topic>Female</topic><topic>Fetal Growth Retardation - blood</topic><topic>Fetal Growth Retardation - diagnosis</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>L-Lactate Dehydrogenase - blood</topic><topic>Original Paper</topic><topic>Pre-Eclampsia - blood</topic><topic>Pre-Eclampsia - diagnosis</topic><topic>Predictive Value of Tests</topic><topic>Pregnancy</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Sensitivity and Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dacaj, Ramadan</creatorcontrib><creatorcontrib>Izetbegovic, Sebija</creatorcontrib><creatorcontrib>Stojkanovic, Goran</creatorcontrib><creatorcontrib>Dreshaj, Skender</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicinski arhiv</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dacaj, Ramadan</au><au>Izetbegovic, Sebija</au><au>Stojkanovic, Goran</au><au>Dreshaj, Skender</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction</atitle><jtitle>Medicinski arhiv</jtitle><addtitle>Med Arch</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>70</volume><issue>1</issue><spage>44</spage><epage>47</epage><pages>44-47</pages><issn>0350-199X</issn><eissn>1986-5961</eissn><abstract>The aim of this study was to evaluate biochemical parameters in serum of women with preeclampsia and IUGR.
A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=60). Outcome measures were following values of biochemical parameters in serum of mother and fetuses: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), bilirubin (indirect and direct) and cholesterol. A blood for analysis was drawn from the cubital vein of mothers and the umbilical vein of the fetuses during delivery period.
The mean of maternal age was 30.0±6.1 years in women with preeclampsia and IUGR and 28.1±5.1 years in healthy pregnant women, p > 0.05. The most of women with preeclampsia and IUGR had grade III of placental maturation (48.3%). There is a significant association between the placental maturation and the diagnosis, p < 0.001. There was a statistically significant difference in body mass of newborns between IUGR and non IUGR groups, p < 0.001. There was a significant statistically difference in serum value of AST, ALT, LDH and total cholesterol between women with preeclampsia and IUGR and healthy pregnant women (all p < 0.001).
Measurement of AST, ALT, LDH, and total cholesterol in serum of pregnant women and newborns with IUGR allows the differentiation and threatening risk of perinatal complications due to hypoxia.</abstract><cop>Bosnia and Herzegovina</cop><pub>Academy of Medical Sciences of Bosnia and Herzegovina</pub><pmid>26980931</pmid><doi>10.5455/medarh.2016.70.44-47</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0350-199X |
| ispartof | Medicinski arhiv, 2016-02, Vol.70 (1), p.44-47 |
| issn | 0350-199X 1986-5961 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4779350 |
| source | MEDLINE; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adult Alanine Transaminase - blood Aspartate Aminotransferases - blood Bilirubin - blood Biomarkers - blood Birth Weight Body Mass Index Cholesterol - blood Female Fetal Growth Retardation - blood Fetal Growth Retardation - diagnosis Humans Infant, Newborn L-Lactate Dehydrogenase - blood Original Paper Pre-Eclampsia - blood Pre-Eclampsia - diagnosis Predictive Value of Tests Pregnancy Prognosis Prospective Studies Sensitivity and Specificity |
| title | Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T02%3A03%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Elevated%20Liver%20Enzymes%20in%20Cases%20of%20Preeclampsia%20and%20Intrauterine%20Growth%20Restriction&rft.jtitle=Medicinski%20arhiv&rft.au=Dacaj,%20Ramadan&rft.date=2016-02-01&rft.volume=70&rft.issue=1&rft.spage=44&rft.epage=47&rft.pages=44-47&rft.issn=0350-199X&rft.eissn=1986-5961&rft_id=info:doi/10.5455/medarh.2016.70.44-47&rft_dat=%3Cproquest_pubme%3E3959662951%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1767066120&rft_id=info:pmid/26980931&rfr_iscdi=true |