Local iron homeostasis in the breast ductal carcinoma microenvironment

While the deregulation of iron homeostasis in breast epithelial cells is acknowledged, iron-related alterations in stromal inflammatory cells from the tumor microenvironment have not been explored. Immunohistochemistry for hepcidin, ferroportin 1 (FPN1), transferrin receptor 1 (TFR1) and ferritin (F...

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Veröffentlicht in:	BMC cancer 2016-03, Vol.16 (185), p.187-187, Article 187
Hauptverfasser:	Marques, Oriana, Porto, Graça, Rêma, Alexandra, Faria, Fátima, Cruz Paula, Arnaud, Gomez-Lazaro, Maria, Silva, Paula, Martins da Silva, Berta, Lopes, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens, CD - genetics Antigens, CD - metabolism Biomarkers Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Carcinoma Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - pathology Cation Transport Proteins - genetics Cation Transport Proteins - metabolism Cloning Female Ferritin Flow Cytometry Gene Expression Genotype & phenotype Hepcidins - genetics Hepcidins - metabolism Homeostasis Humans Immunohistochemistry Iron - metabolism Lymph Nodes - metabolism Lymph Nodes - pathology Lymphocytes Macrophages Pathology Receptors, Transferrin - genetics Receptors, Transferrin - metabolism Tumor Burden Tumor Microenvironment
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