Eicosopentaneoic Acid and Other Free Fatty Acid Receptor Agonists Inhibit Lysophosphatidic Acid- and Epidermal Growth Factor-Induced Proliferation of Human Breast Cancer Cells

Many key actions of ω-3 (n-3) fatty acids have recently been shown to be mediated by two G protein-coupled receptors (GPCRs) in the free fatty acid receptor (FFAR) family, FFA1 (GPR40) and FFA4 (GPR120). n-3 Fatty acids inhibit proliferation of human breast cancer cells in culture and in animals. In...

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Veröffentlicht in:	Journal of clinical medicine 2016-01, Vol.5 (2), p.16
Hauptverfasser:	Hopkins, Mandi M, Zhang, Zhihong, Liu, Ze, Meier, Kathryn E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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