Sequencing of PCR amplified HBV DNA pre-c and c regions in the 2.2.15 cells and antiviral action by targeted antisense oligonucleotide directed against sequence

AIM:To study the specific inhibition of HBV gene expression by liver-targeting antisense oligonucleotide (ASON) directed against pre-c and cregious in a sequence specific manner.METHODS:According to the result of direct sequencing of PCR amplified products, a 16 mer phosphorothioate analogue of the...

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Veröffentlicht in:	World journal of gastroenterology : WJG 1998-10, Vol.4 (5), p.434-436
Hauptverfasser:	Zhoug, Sen, Wen, Shou-Ming, Zhang, Ding-Feng, Wang, Quan-Li, Wang, Seng-Qi, Ren, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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