The Na+‐Taurocholate Cotransporting Polypeptide Traffics with the Epidermal Growth Factor Receptor

Na+‐taurocholate cotransporting polypeptide (ntcp) mediates bile acid transport, also serving as the hepatitis B virus receptor. It traffics in vesicles along microtubules, requiring activity of protein kinase C (PKC)ζ for motility. We have now found that the epidermal growth factor receptor (EGFR)...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2016-03, Vol.17 (3), p.230-244
Hauptverfasser:	Wang, Xintao, Wang, Pijun, Wang, Wenjun, Murray, John W., Wolkoff, Allan W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile bile acid Cell Line, Tumor drug transport endosome Endosomes - metabolism Epidermal growth factor hepatitis B virus (HBV) Humans Kinases Liver Lysosomes - metabolism microtubule Organic Anion Transporters, Sodium-Dependent - metabolism Protein Kinase C - metabolism Protein Transport Receptor, Epidermal Growth Factor - metabolism Secretory Vesicles - metabolism Symporters - metabolism
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