Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis

The development of the hematopoietic system is a dynamic process that is controlled by the interplay between transcriptional and epigenetic networks to determine cellular identity. These networks are critical for lineage specification and are frequently dysregulated in leukemias. Here, we identified...

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Veröffentlicht in:The Journal of clinical investigation 2016-03, Vol.126 (3), p.905-920
Hauptverfasser: Andricovich, Jaclyn, Kai, Yan, Peng, Weiqun, Foudi, Adlen, Tzatsos, Alexandros
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Sprache:eng
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