Resveratrol ameliorates fibrosis and inflammation in a mouse model of nonalcoholic steatohepatitis

The natural polyphenol compound resveratrol (RSV) is considered to have a broad spectrum of beneficial biological activities upon human health. However, the exact effect of RSV on steatosis (a phenotype of non-alcoholic fatty liver [NAFL]) or fibrosis and inflammation (major phenotypes of non-alcoho...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2016-02, Vol.6 (1), p.22251-22251, Article 22251
Hauptverfasser:	Kessoku, Takaomi, Imajo, Kento, Honda, Yasushi, Kato, Takayuki, Ogawa, Yuji, Tomeno, Wataru, Kato, Shingo, Mawatari, Hironori, Fujita, Koji, Yoneda, Masato, Nagashima, Yoji, Saito, Satoru, Wada, Koichiro, Nakajima, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	13/21 38/90 64/60 692/4020/4021/1607/1605 692/4020/4021/1607/2751 82/51 82/83 Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology CD14 antigen Cell Line Disease Models, Animal Fatty liver Fibrosis Fibrosis - genetics Fibrosis - metabolism Fibrosis - prevention & control Fluorescent Antibody Technique Gene Expression - drug effects High fat diet Humanities and Social Sciences Humans Immunoblotting Inflammation Inflammation - genetics Inflammation - metabolism Inflammation - prevention & control Interleukin-6 - genetics Interleukin-6 - metabolism Kupffer cells Lipopolysaccharide Receptors - genetics Lipopolysaccharide Receptors - metabolism Lipopolysaccharides Male Mice, Inbred C57BL multidisciplinary Non-alcoholic Fatty Liver Disease - chemically induced Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - prevention & control Resveratrol Reverse Transcriptase Polymerase Chain Reaction Rodents Science Signal Transduction - drug effects STAT3 Transcription Factor - metabolism Steatosis Stilbenes - pharmacology Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!