Local and systemic vasodilatory effects of low molecular weight S-nitrosothiols

S-nitrosothiols (SNOs) such as S-nitroso-L-cysteine (L-cysNO) are endogenous compounds with potent vasodilatory activity. During circulation in the blood, the NO moiety can be exchanged among various thiol-containing compounds by S-transnitrosylation, resulting in SNOs with differing capacities to e...

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Veröffentlicht in:	Free radical biology & medicine 2016-02, Vol.91, p.215-223
Hauptverfasser:	Liu, Taiming, Schroeder, Hobe J., Wilson, Sean M., Terry, Michael H., Romero, Monica, Longo, Lawrence D., Power, Gordon G., Blood, Arlin B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Cysteine - analogs & derivatives Cysteine - pharmacology Cysteine - physiology Drug Evaluation, Preclinical Membrane permeability Molecular Weight Muscle, Smooth, Vascular - cytology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - physiology Nitric oxide Nitric Oxide - metabolism S-nitrosothiol S-Nitrosothiols - pharmacology S-transnitrosylation Sheep Vasodilation Vasodilation - drug effects Vasodilator Agents - pharmacology
Online-Zugang:	Volltext
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