Calstabin 2: An important regulator for learning and memory in mice

Calstabin2, also named FK506 binding protein 12.6 (FKBP12.6), is a subunit of ryanodine receptor subtype 2 (RyR2) macromolecular complex, which is an intracellular calcium channel and abundant in the brain. Previous studies identified a role of leaky neuronal RyR2 in posttraumatic stress disorder (P...

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Veröffentlicht in:	Scientific reports 2016-02, Vol.6 (1), p.21087-21087, Article 21087
Hauptverfasser:	Yuan, Qi, Deng, Ke-Yu, Sun, Le, Chi, Shaopeng, Yang, Zhiguang, Wang, Jun, Xin, Hong-Bo, Wang, Xiaoqun, Ji, Guangju
Format:	Artikel
Sprache:	eng
Schlagworte:	13/2 13/31 14/19 14/34 631/378/1595/1554 64/110 64/60 692/617/375 9/30 Animals Apoptosis Calcium (intracellular) Calcium channels Calcium currents Cognitive ability Excitability Hippocampus Hippocampus - cytology Hippocampus - metabolism Humanities and Social Sciences Leak channels Learning Long term memory Long-term potentiation Long-Term Potentiation - physiology Macromolecules Maze Learning - physiology Memory Memory - physiology Mice Mice, Knockout multidisciplinary Post traumatic stress disorder Potassium currents Rodents Ryanodine receptors Science Tacrolimus Tacrolimus Binding Proteins - genetics Tacrolimus Binding Proteins - metabolism Tacrolimus-binding protein
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