Chemical Fluorescent Probe for Detection of Aβ Oligomers

Aggregation of amyloid β-peptide (Aβ) is implicated in the pathology of Alzheimer’s disease (AD), with the soluble, Aβ oligomeric species thought to be the critical pathological species. Identification and characterization of intermediate species formed during the aggregation process is crucial to t...

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Veröffentlicht in:	Journal of the American Chemical Society 2015-10, Vol.137 (42), p.13503-13509
Hauptverfasser:	Teoh, Chai Lean, Su, Dongdong, Sahu, Srikanta, Yun, Seong-Wook, Drummond, Eleanor, Prelli, Frances, Lim, Sulgi, Cho, Sunhee, Ham, Sihyun, Wisniewski, Thomas, Chang, Young-Tae
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta-Peptides - analysis Amyloid beta-Peptides - chemistry Amyloid beta-Peptides - classification Animals Brain - pathology Disease Models, Animal Fluorescent Dyes - chemistry Mice Models, Molecular Thermodynamics
Online-Zugang:	Volltext
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