Alcohol, drinking pattern and all-cause, cardiovascular and alcohol-related mortality in Eastern Europe
Alcohol has been implicated in the high mortality in Central and Eastern Europe but the magnitude of its effect, and whether it is due to regular high intake or episodic binge drinking remain unclear. The aim of this paper was to estimate the contribution of alcohol to mortality in four Central and...
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| Veröffentlicht in: | European journal of epidemiology 2016-01, Vol.31 (1), p.21-30 |
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| creator | Bobak, Martin Malyutina, Sofia Horvat, Pia Pajak, Andrzej Tamosiunas, Abdonas Kubinova, Ruzena Simonova, Galina Topor-Madry, Roman Peasey, Anne Pikhart, Hynek Marmot, Michael G. |
| description | Alcohol has been implicated in the high mortality in Central and Eastern Europe but the magnitude of its effect, and whether it is due to regular high intake or episodic binge drinking remain unclear. The aim of this paper was to estimate the contribution of alcohol to mortality in four Central and Eastern European countries. We used data from the Health, Alcohol and Psychosocial factors in Eastern Europe is a prospective multi-centre cohort study in Novosibirsk (Russia), Krakow (Poland), Kaunas (Lithuania) and six Czech towns. Random population samples of 34,304 men and women aged 45-69 years in 2002-2005 were followed up for a median 7 years. Drinking volume, frequency and pattern were estimated from the graduated frequency questionnaire. Deaths were ascertained using mortality registers. In 230,246 person-years of follow-up, 2895 participants died from all causes, 1222 from cardiovascular diseases (CVD), 672 from coronary heart disease (CHD) and 489 from pre-defined alcohol-related causes (ARD). In fully-adjusted models, abstainers had 30-50 % increased mortality risk compared to light-to-moderate drinkers. Adjusted hazard ratios (HR) in men drinking on average ≥60 g of ethanol/day(3 % of men) were 1.23 (95 % CI 0.95-1.59) for all-cause, 1.38 (0.95-2.02) for CVD, 1.64 (1.02-2.64) for CHD and 2.03 (1.28-3.23) for ARD mortality. Corresponding HRs in women drinking on average ≥20 g/day (2 % of women) were 1.92 (1.25-2.93), 1.74 (0.76-3.99), 1.39 (0.34-5.76) and 3.00 (1.26-7.10). Binge drinking increased ARD mortality in men only. Mortality was associated with high average alcohol intake but not binge drinking, except for ARD in men. |
| doi_str_mv | 10.1007/s10654-015-0092-8 |
| format | Article |
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The aim of this paper was to estimate the contribution of alcohol to mortality in four Central and Eastern European countries. We used data from the Health, Alcohol and Psychosocial factors in Eastern Europe is a prospective multi-centre cohort study in Novosibirsk (Russia), Krakow (Poland), Kaunas (Lithuania) and six Czech towns. Random population samples of 34,304 men and women aged 45-69 years in 2002-2005 were followed up for a median 7 years. Drinking volume, frequency and pattern were estimated from the graduated frequency questionnaire. Deaths were ascertained using mortality registers. In 230,246 person-years of follow-up, 2895 participants died from all causes, 1222 from cardiovascular diseases (CVD), 672 from coronary heart disease (CHD) and 489 from pre-defined alcohol-related causes (ARD). In fully-adjusted models, abstainers had 30-50 % increased mortality risk compared to light-to-moderate drinkers. Adjusted hazard ratios (HR) in men drinking on average ≥60 g of ethanol/day(3 % of men) were 1.23 (95 % CI 0.95-1.59) for all-cause, 1.38 (0.95-2.02) for CVD, 1.64 (1.02-2.64) for CHD and 2.03 (1.28-3.23) for ARD mortality. Corresponding HRs in women drinking on average ≥20 g/day (2 % of women) were 1.92 (1.25-2.93), 1.74 (0.76-3.99), 1.39 (0.34-5.76) and 3.00 (1.26-7.10). Binge drinking increased ARD mortality in men only. Mortality was associated with high average alcohol intake but not binge drinking, except for ARD in men.</description><identifier>ISSN: 0393-2990</identifier><identifier>EISSN: 1573-7284</identifier><identifier>DOI: 10.1007/s10654-015-0092-8</identifier><identifier>PMID: 26467937</identifier><identifier>CODEN: EJEPE8</identifier><language>eng</language><publisher>Dordrecht: Springer</publisher><subject>Adult ; Aged ; Alcohol drinking ; Alcohol Drinking - adverse effects ; Alcohol Drinking - mortality ; Alcohol use ; Alcoholic beverages ; Alcoholic Intoxication - complications ; Alcoholic Intoxication - mortality ; Alcoholism - complications ; Alcoholism - mortality ; Alcohols ; Binge drinking ; Binge Drinking - complications ; Binge Drinking - mortality ; Cardiology ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - mortality ; Cause of Death ; Causes of death ; Cohort Studies ; Epidemiology ; Ethanol ; Europe, Eastern - epidemiology ; Female ; Health risks ; Humans ; Infectious Diseases ; Male ; Medicine ; Medicine & Public Health ; Men ; Middle Aged ; MORTALITY ; Mortality rates ; Mortality risk ; Oncology ; Proportional Hazards Models ; Public Health ; Risk Assessment ; Risk Factors ; Time Factors ; Women</subject><ispartof>European journal of epidemiology, 2016-01, Vol.31 (1), p.21-30</ispartof><rights>Springer Science+Business Media 2016</rights><rights>The Author(s) 2015</rights><rights>Springer Science+Business Media Dordrecht 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c661t-6fb5d97b8f38f320d531babeddff1f588c0b1d9c87d1235ff258503d423e77133</citedby><cites>FETCH-LOGICAL-c661t-6fb5d97b8f38f320d531babeddff1f588c0b1d9c87d1235ff258503d423e77133</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44851715$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44851715$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,780,784,803,885,27922,27923,41486,42555,51317,58015,58248</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26467937$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bobak, Martin</creatorcontrib><creatorcontrib>Malyutina, Sofia</creatorcontrib><creatorcontrib>Horvat, Pia</creatorcontrib><creatorcontrib>Pajak, Andrzej</creatorcontrib><creatorcontrib>Tamosiunas, Abdonas</creatorcontrib><creatorcontrib>Kubinova, Ruzena</creatorcontrib><creatorcontrib>Simonova, Galina</creatorcontrib><creatorcontrib>Topor-Madry, Roman</creatorcontrib><creatorcontrib>Peasey, Anne</creatorcontrib><creatorcontrib>Pikhart, Hynek</creatorcontrib><creatorcontrib>Marmot, Michael G.</creatorcontrib><title>Alcohol, drinking pattern and all-cause, cardiovascular and alcohol-related mortality in Eastern Europe</title><title>European journal of epidemiology</title><addtitle>Eur J Epidemiol</addtitle><addtitle>Eur J Epidemiol</addtitle><description>Alcohol has been implicated in the high mortality in Central and Eastern Europe but the magnitude of its effect, and whether it is due to regular high intake or episodic binge drinking remain unclear. The aim of this paper was to estimate the contribution of alcohol to mortality in four Central and Eastern European countries. We used data from the Health, Alcohol and Psychosocial factors in Eastern Europe is a prospective multi-centre cohort study in Novosibirsk (Russia), Krakow (Poland), Kaunas (Lithuania) and six Czech towns. Random population samples of 34,304 men and women aged 45-69 years in 2002-2005 were followed up for a median 7 years. Drinking volume, frequency and pattern were estimated from the graduated frequency questionnaire. Deaths were ascertained using mortality registers. In 230,246 person-years of follow-up, 2895 participants died from all causes, 1222 from cardiovascular diseases (CVD), 672 from coronary heart disease (CHD) and 489 from pre-defined alcohol-related causes (ARD). In fully-adjusted models, abstainers had 30-50 % increased mortality risk compared to light-to-moderate drinkers. Adjusted hazard ratios (HR) in men drinking on average ≥60 g of ethanol/day(3 % of men) were 1.23 (95 % CI 0.95-1.59) for all-cause, 1.38 (0.95-2.02) for CVD, 1.64 (1.02-2.64) for CHD and 2.03 (1.28-3.23) for ARD mortality. Corresponding HRs in women drinking on average ≥20 g/day (2 % of women) were 1.92 (1.25-2.93), 1.74 (0.76-3.99), 1.39 (0.34-5.76) and 3.00 (1.26-7.10). Binge drinking increased ARD mortality in men only. Mortality was associated with high average alcohol intake but not binge drinking, except for ARD in men.</description><subject>Adult</subject><subject>Aged</subject><subject>Alcohol drinking</subject><subject>Alcohol Drinking - adverse effects</subject><subject>Alcohol Drinking - mortality</subject><subject>Alcohol use</subject><subject>Alcoholic beverages</subject><subject>Alcoholic Intoxication - complications</subject><subject>Alcoholic Intoxication - mortality</subject><subject>Alcoholism - complications</subject><subject>Alcoholism - mortality</subject><subject>Alcohols</subject><subject>Binge drinking</subject><subject>Binge Drinking - complications</subject><subject>Binge Drinking - mortality</subject><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cardiovascular Diseases - mortality</subject><subject>Cause of Death</subject><subject>Causes of death</subject><subject>Cohort Studies</subject><subject>Epidemiology</subject><subject>Ethanol</subject><subject>Europe, Eastern - epidemiology</subject><subject>Female</subject><subject>Health risks</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Men</subject><subject>Middle Aged</subject><subject>MORTALITY</subject><subject>Mortality rates</subject><subject>Mortality risk</subject><subject>Oncology</subject><subject>Proportional Hazards Models</subject><subject>Public Health</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Time 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drinking pattern and all-cause, cardiovascular and alcohol-related mortality in Eastern Europe</title><author>Bobak, Martin ; Malyutina, Sofia ; Horvat, Pia ; Pajak, Andrzej ; Tamosiunas, Abdonas ; Kubinova, Ruzena ; Simonova, Galina ; Topor-Madry, Roman ; Peasey, Anne ; Pikhart, Hynek ; Marmot, Michael G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c661t-6fb5d97b8f38f320d531babeddff1f588c0b1d9c87d1235ff258503d423e77133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Alcohol drinking</topic><topic>Alcohol Drinking - adverse effects</topic><topic>Alcohol Drinking - mortality</topic><topic>Alcohol use</topic><topic>Alcoholic beverages</topic><topic>Alcoholic Intoxication - complications</topic><topic>Alcoholic Intoxication - mortality</topic><topic>Alcoholism - complications</topic><topic>Alcoholism - mortality</topic><topic>Alcohols</topic><topic>Binge drinking</topic><topic>Binge Drinking - complications</topic><topic>Binge Drinking - mortality</topic><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cardiovascular Diseases - mortality</topic><topic>Cause of Death</topic><topic>Causes of death</topic><topic>Cohort Studies</topic><topic>Epidemiology</topic><topic>Ethanol</topic><topic>Europe, Eastern - epidemiology</topic><topic>Female</topic><topic>Health risks</topic><topic>Humans</topic><topic>Infectious Diseases</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Men</topic><topic>Middle Aged</topic><topic>MORTALITY</topic><topic>Mortality rates</topic><topic>Mortality risk</topic><topic>Oncology</topic><topic>Proportional Hazards Models</topic><topic>Public Health</topic><topic>Risk Assessment</topic><topic>Risk 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journal of epidemiology</jtitle><stitle>Eur J Epidemiol</stitle><addtitle>Eur J Epidemiol</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>31</volume><issue>1</issue><spage>21</spage><epage>30</epage><pages>21-30</pages><issn>0393-2990</issn><eissn>1573-7284</eissn><coden>EJEPE8</coden><abstract>Alcohol has been implicated in the high mortality in Central and Eastern Europe but the magnitude of its effect, and whether it is due to regular high intake or episodic binge drinking remain unclear. The aim of this paper was to estimate the contribution of alcohol to mortality in four Central and Eastern European countries. We used data from the Health, Alcohol and Psychosocial factors in Eastern Europe is a prospective multi-centre cohort study in Novosibirsk (Russia), Krakow (Poland), Kaunas (Lithuania) and six Czech towns. Random population samples of 34,304 men and women aged 45-69 years in 2002-2005 were followed up for a median 7 years. Drinking volume, frequency and pattern were estimated from the graduated frequency questionnaire. Deaths were ascertained using mortality registers. In 230,246 person-years of follow-up, 2895 participants died from all causes, 1222 from cardiovascular diseases (CVD), 672 from coronary heart disease (CHD) and 489 from pre-defined alcohol-related causes (ARD). In fully-adjusted models, abstainers had 30-50 % increased mortality risk compared to light-to-moderate drinkers. Adjusted hazard ratios (HR) in men drinking on average ≥60 g of ethanol/day(3 % of men) were 1.23 (95 % CI 0.95-1.59) for all-cause, 1.38 (0.95-2.02) for CVD, 1.64 (1.02-2.64) for CHD and 2.03 (1.28-3.23) for ARD mortality. Corresponding HRs in women drinking on average ≥20 g/day (2 % of women) were 1.92 (1.25-2.93), 1.74 (0.76-3.99), 1.39 (0.34-5.76) and 3.00 (1.26-7.10). Binge drinking increased ARD mortality in men only. Mortality was associated with high average alcohol intake but not binge drinking, except for ARD in men.</abstract><cop>Dordrecht</cop><pub>Springer</pub><pmid>26467937</pmid><doi>10.1007/s10654-015-0092-8</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Alcohol drinking Alcohol Drinking - adverse effects Alcohol Drinking - mortality Alcohol use Alcoholic beverages Alcoholic Intoxication - complications Alcoholic Intoxication - mortality Alcoholism - complications Alcoholism - mortality Alcohols Binge drinking Binge Drinking - complications Binge Drinking - mortality Cardiology Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - etiology Cardiovascular Diseases - mortality Cause of Death Causes of death Cohort Studies Epidemiology Ethanol Europe, Eastern - epidemiology Female Health risks Humans Infectious Diseases Male Medicine Medicine & Public Health Men Middle Aged MORTALITY Mortality rates Mortality risk Oncology Proportional Hazards Models Public Health Risk Assessment Risk Factors Time Factors Women |
| title | Alcohol, drinking pattern and all-cause, cardiovascular and alcohol-related mortality in Eastern Europe |
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