Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice

E2F3 and MYC are transcription factors that control cellular proliferation. To study their mechanism of action in the context of a regenerating tissue, we isolated both proliferating (crypts) and non-dividing (villi) cells from wild-type and Rb depleted small intestines of mice and performed ChIP-ex...

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Veröffentlicht in:	Scientific data 2016-02, Vol.3 (1), p.160008-160008, Article 160008
Hauptverfasser:	Tang, Xing, Liu, Huayang, Srivastava, Arunima, Pécot, Thierry, Chen, Zhong, Wang, Qianben, Huang, Kun, Sáenz-Robles, Maria Teresa, Cantalupo, Paul, Pipas, James, Leone, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/2091 631/1647/2017/2079 631/1647/2217/2088 631/337/572/2102 631/337/641/1655 Animal genetics Animals Binding Sites Biochemistry, Molecular Biology Cell Proliferation Chromatin - genetics Chromatin - metabolism Chromatin Immunoprecipitation Data Descriptor E2F3 Transcription Factor - genetics E2F3 Transcription Factor - metabolism Genes, myc Genes, Retinoblastoma Genetics Humanities and Social Sciences Intestine, Small - cytology Intestine, Small - metabolism Life Sciences Mice Molecular biology multidisciplinary Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Retinoblastoma Protein - genetics Retinoblastoma Protein - metabolism Science Transcriptome
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